Buffalo Bills 2023 NFL Season Betting Guide

Buffalo Bills 2023 NFL Season Betting Guide

Prior to the start of every new NFL season, we all have a pretty good idea of who we think will be in contention to win the Super Bowl. The season seldom plays out as expected, though, and while one of the favorites may end up lifting the Lombardi Trophy, others will stumble and fall along the way. After all, only one team can win it all. Looking ahead to the coming season, there are some familiar teams at the top of the bookies board, with the Buffalo Bills once again among the favorites to end the season as the champions. They certainly looked well equipped on both sides of the football, but they have some tough tests ahead of them as they look to make the postseason, so let’s look at some of the bigger challenges on their NFL schedule to consider in your NFL betting odds.


Buffalo Bills: Top Games to Bet in all Regular Season Week 1-17| MyBookie NFL Betting Predictions

2023 NFL season | 104th season of National Football League in the United States
September 7, 2023–February 11, 2024


Week 1 at New York Jets

When: Monday, September 11, 8:15pm ET
Where: MetLife Stadium, East Rutherford, NJ
TV/Streaming: ESPN/ABC

The AFC East looks to be a little tougher this season, with the Jets, who now have Aaron Rodgers under center, expected to be a whole lot better. We will get a good idea of just how good they might be in the opening week of the season. This is a game that might well set the tone for the East this season.

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MyBookie Betting Lines for the Game


Week 4 Vs Miami Dolphins

When: Sunday, October 1, 1:00pm ET
Where: Highmark Stadium, Orchard Park, NY
TV/Streaming: CBS

I promise that all the big games listed here are not divisional matchups, but the Bills have a pair of big ones in the opening month of the season. I was going to add the trip to Miami later in the season to this list, but I think this one might be bigger. This will be a chance for Buffalo to assert some early divisional dominance.

Bet Bills vs Dophins to Win Today
MyBookie Betting Lines for the Game


Week 5 Vs Jacksonville Jaguars

When: Sunday, October 8, 9:30am ET
Where: Tottenham Hotspur Stadium, London, England
TV/Streaming: NFLN

In recent years, this would have been viewed as a gimme type of game for the Bills, but the Jaguars are a team on the rise. This is still a game that Buffalo would expect to win in their own building, but it’s also a potential banana peel, assuming that the Jags continue their upward momentum in 2023.

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MyBookie Betting Lines for the Game


Week 9 at Cincinnati Bengals

When: Sunday, November 5, 8:20pm ET
Where: Paycor Stadium, Cincinnati, OH
TV/Streaming: NBC

There are some who believe that the AFC is a 3-way race between the Bills, Chiefs, and Bengals. If that is indeed the case, then this game is absolutely huge, as it may be a preview of a playoff matchup later in the year. This is about as tough a road game as you can ask for and one that may affect the conference seeding.

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MyBookie Betting Lines for the Game


Week 12 at Philadelphia Eagles

When: Sunday, November 26, 4:25pm ET
Where: Lincoln Financial Field, Philadelphia, PA
TV/Streaming: CBS

The Bills have a tough second half of the season, with yet another brutal road trip coming right before their bye week. The Eagles went to the Super Bowl last season and are considered the favorites to win the NFC. Could this be a potential Super Bowl preview?

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MyBookie Betting Lines for the Game


Week 14 Vs Kansas City Chiefs

When: Sunday, December 10, 4:25pm ET
Where: Arrowhead Stadium, Kansas City, MO
TV/Streaming: CBS

In the last couple of seasons, the meetings between these two teams have been nothing short of legendary. The Bills and Chiefs are arguably the two best teams in the NFL and until that changes, this is a matchup that we will all have circled on the schedule.

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MyBookie Betting Lines for the Game


Week 15 Vs Dallas Cowboys

When: Sunday, December 17, 4:25pm ET
Where: Highmark Stadium, Orchard Park, NY
TV/Streaming: FOX

The last game on this list was a bit of a coin flip between this one and the game against the LA Chargers in Week 16. I went with the Cowboys, simply because I think this is a bigger test for the Bills, as well as being the more glamorous of the two games.

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MyBookie Betting Lines for the Game


2024 NFL Conference Championship Odds

Odds to Win 2024 AFC Championship
AFC Team Odds
Baltimore Ravens +125
Kansas City Chiefs +425
AFC Lines to Win
Odds to Win 2024 NFC Championship
NFC Team Odds
San Francisco 49ers -130
Detroit Lions +900
NFC Lines to Win

2024 NFL Calendar by Week


I have read enough, I need to place my bet now. What to do?

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