There is nothing quite like the opening week of the NFL season. It’s a time when fans of every team are excited about the prospects of their squad, although many will see their hopes very quickly dashed in the opening weeks. One of the fun things to do when looking ahead at the upcoming season is to try and identify those teams that might find lightning in a bottle and go on an unexpected run. There are always one or two of those team every season and we will almost certainly talk about them as the season progresses. For now, it’s all about looking at the Week 1 schedule and trying to identify some winning picks, which is never easy in the early part of the season. For the purposes of this NFL Betting piece, we are going to focus on our O/U selections for Week 1, so let’s get to it.
Week 1 O/U Picks for the 2021 Season | NFL Betting
Dallas Cowboys at Tampa Bay Buccaneers (Under 52)
There seems to be a feeling that the Buccaneers are going to come out and dominate right off the bat this season. With so many new pieces in 2020, it took them some time to get rolling, so they certainly don’t have that excuse this season. As for the Cowboys, they are going to be looking at Dak Prescott and hoping that he is fully recovered from a brutal season-ending injury. Word is that he is good to go, but actual game time looks a whole lot different from preseason training, much of which he sat out through a shoulder injury. That has me concerned about how much offense we might see from the Cowboys this week. Add that to the fact that 5 of the last 6 meetings between these two teams have gone UNDER and you have me leaning towards the UNDER in this one.
Pittsburgh Steelers at Buffalo Bills (Under 48 ½)
A lot of people, myself included, are looking at the Buffalo Bills as a legitimate Super Bowl threat this season. While this is still a very tricky opening game for them, this is a Steelers team that looks to be in a bit of a transition mode. Salary cap issues and the holdout of TJ Watt are just a couple of areas of concern that makes this season look like a potential down year for Pittsburgh. In particular, their O-Line looks a little weak, which could make racking up points difficult. Even if Watt does not play, their D is still good enough to limit what the Bills can do. All of that adds up to this one going UNDER the point total.
Cleveland Browns at Kansas City Chiefs (Over 54 ½)
It’s tough to do, but if you believe the hype coming out of Cleveland, then we might well potentially be looking at an AFC Conference Championship Game preview in Week 1 of the season. The Browns made a big leap forward last season, getting to the playoffs and winning a game. They figure to be stronger this year, but this is certainly a very good litmus test for where they are at. The Chiefs should be great again and will be an offensive force to be reckoned with. This is a game that could well turn into a shootout, and with KB seeing 14 of their last 20 games played in September going OVER, the chances of this bet coming in look good.
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