2022 NFL Spread Betting Picks for Top Games of Week 2

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If Week 1 is anything to go by, then we are in for something pretty special this season in the NFL. The Buffalo Bills look to be very much as advertised, while the Kansas City Chiefs also looked to be as explosive as ever. It was a rough start for the Bengals, who went to the Super Bowl last season, going down at home to the Steelers, while Russell Wilson’s debut with the Denver Broncos was spoiled with a loss on the road in his old home of Seattle. There were countless other storylines to discuss, but it’s now time to look ahead to Week 2 to see if we can come up with some winning picks. Let’s get the ball rolling with some NFL Betting againts the spread picks for Week 2.

Against The Spread Early Picks Must Wager On for NFL Week 2

Cincinnati Bengals (-8) at Dallas Cowboys

As we already mentioned, the Bengals got off to a losing start, with turnovers doing them in against the Steelers. What we have learned from Joe Burrow in his short time as the Bengals QB is that he is able to quickly shake off such setbacks. The question here is whether the Cowboys can do the same, as they were the only team not to score a TD in the opening week of the season, while also losing Dak Prescott for 6-8 weeks through injury. It’s not the ideal start for Dallas and I think things are about to get worse. The Bengals have covered in 8 of their last 10, which makes them a very good bet here.

Washington Commander at Detroit Lions (-2 ½)

It’s not often we get to see the Detroit Lions enter a game as the favorite, but that is exactly what they are at home to the Commanders in Week 2. The Lions may have lost in Week 1, but they showed some serious battling ability against a very good Philly team, going down 38-35 in an absolute thriller. The Commanders won 28-22 over Jacksonville, which is nothing to get too excited about, although they will be happy to see their season get off to a winning start. As you can see from the odds, the bookies like this to be a tight affair, but I am leaning towards the Lions to win and cover. They have gone 6-1 ATS in their last 7 home games, which makes them a tempting bet this weekend.

Carolina Panthers at New York Giants (-2 ½)

Things did not look good for the New York Giants in Week 1, as they went into half-time in a 13-0 hole against the Tennessee Titans. Most us of probably wrote them off at that point, but they bounced back in the second half and came away with an unexpected 21-20 win, with Saquon Barkley looking to be back to his brilliant best. Baker Mayfield failed to get revenge against hos old team, with the Panthers going down to the Browns in Week 1. The Panthers are now a miserable 1-9 ATS in their last 10 games, which has me leaning in the direction of the Giants this coming Sunday.