NFL Week 1 Betting Predictions: Underdog Teams to Wager On

NFL Week 1 Betting Predictions: Underdog Teams to Wager On

The National Football League’s new season is almost here. Often, Week 1 is the perfect time to score money on underdogs. Check out the list of this season’s top Week 1 underdog plays so you can make your bets against the NFL odds for the rapidly approaching 2021-22 Season.

NFL Underdogs To Bet On in Week 1

2021 NFL Week 1

  • When: Thursday, Sep. 9 – Monday, Sep. 13

Pittsburgh Steelers +7 at Buffalo Bills

  • When: Sunday, Sep. 12

Buffalo should beat the Steelers, but this feels like a lot of points. Yes, the Bills are at home, but the Steelers could be underrated. Not only that, but Pittsburgh coach Mike Tomlin is a master at developing a game plan for a specific opponent. Tomlin will ensure Pittsburgh keeps this closer than the spread.  

Jacksonville Jaguars at Houston Texans +3

  • When: Sunday, Sep. 12

Is it us, or is everyone reading too much into the Jaguars’ drafting Trevor Lawrence and hiring Urban Meyer to coach? College coaches usually struggle in the NFL. Houston will start either Deshaun Watson or Tyrod Taylor. Either way, the Texans have an edge at the quarterback position because Lawrence faces a decent Houston defense. Consider backing the Texans on the moneyline. 

Minnesota Vikings at Cincinnati Bengals +3 ½ 

  • When: Sunday, Sep. 12

The Vikings showed no heart in their first preseason game. Kirk Cousins refuses to get the vaccine, and coach Mike Zimmer looks tired. Bengals quarterback Joe Burrow is fired up after spending the second-half of his rookie season on the bench. Cincinnati’s defense should also be much improved and the Bengals play this one on their field. Cincinnati could upset Minnesota straight up. 

Cleveland Browns +6 at Kansas City Chiefs

  • When: Sunday, Sep. 12

Sure, the Chiefs are loaded. But KC faces the best rushing team in the NFL in Week 1. Cleveland is a solid squad with a defense on the rise, two starting running backs, and a quarterback in Baker Mayfield who should take the next step. The Browns can win this SU. 

Miami Dolphins +2 ½ at New England Patriots

  • When: Sunday, Sep. 12

The Dolphins are better than the Patriots. Yes, New England signed a couple of strong tight-ends and quarterback Mac Jones has played well in a couple of preseason games. But Miami should have one of the better defenses in the league and the offense should be much improved now that Tua Tagovailoa can throw to his favorite target from Alabama, Jaylen Waddle.  

Green Bay Packers at New Orleans Saints +3

  • When: Sunday, Sep. 12

Green Bay looks like the much better squad. However, Aaron Rodgers doesn’t seem fired about playing this season. Both Jameis Winston and Taysom Hill are decent quarterbacks and NFL analysts aren’t giving the Saints’ defense enough credit. In the Superdome, New Orleans can upset the Packers on the moneyline.  

Chicago Bears +7 at Los Angeles Rams

  • When: Sunday, Sep. 12

With Matthew Stafford, the Rams should contend for the conference title. But this line gives LAR too much credit. NFL handicappers haven’t noticed that Bears’ quarterback Andy Dalton is miles better than Mitch Trubisky. Chicago’s defense remains one of the better units in the league. So even though Da Bears may not win this one, they should cover the spread.  


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