Top MLS Odds: Six Matches to Must Bet On

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Major League Soccer is back. First week soccer odds favor home teams like Atlanta versus San Jose, Philadelphia Union against Columbus, and Austin FC versus St. Louis City. Preseason favorite to win it all Los Angeles FC is a slight chalk over the rival Galaxy. Check out MLS odds, analysis, and free picks for six of this weekend’s best soccer games.

Top 2023 Major League Soccer Betting Games for Weekend | Week 1 MLS Lines

Atlanta United FC -170 vs. San Jose Earthquakes +420

When: Saturday, February 25
Where: Mercedes-Benz Stadium, Atlanta, Georgia

Time: 7:30 PM EST
TV: Apple TV, FOX

Atlanta United doesn’t enter the season playing great. The ATL U ended last MLS season losing 2 straight. Atlanta lost a club friendly match versus Toluca in their last.

San Jose finished with a win and a draw to end their 2022 MLS Season. The Earthquakes appear to have a chance, but this is their first recorded match since October. So Atlanta is the pick.

Soccer Pick: Atlanta United

Philadelphia Union -134 vs. Columbus Crew +380

When: Saturday, February 25
Where: Subaru Park, Chester

Time: 7:30 PM EST
TV: Apple TV

Many expect Philadelphia, like they did last season, to challenge the Los Angeles Football Club in this season’s MLS title game.

Philly Union pushed LAFC big time in that Nov. 5 matchup, scoring 3 goals and falling to Los Angeles via penalty kicks. Columbus forced a draw in the last head-to-head but this happens on Philadelphia’s pitch. The home squad prevails.

Soccer Pick: Philadelphia Union

Austin FC -178 vs. St. Louis City FC +460

When: Saturday, February 25
Where: Q2 Stadium, Austin

Time: 8:30 PM EST
TV: Apple TV

This is St. Louis’ first MLS game. For the City of St. Louis, it’s a time to celebrate. But the road team in this match won’t start their MLS history on a positive note.

Sure, the fact St. Louis is playing is a big deal. However, Austin should be one of Major League Soccer’s best teams. Austin fell to LAFC in their final 2022 match. There’s no shame in that. A 1-1 club friendly draw versus Sacramento Republic should set up the home team for an impressive win in this.

Soccer Pick: Austin FC

LA Galaxy +174 vs. LAFC +155

When: Saturday, February 25
Where: Rose Bowl, Pasadena

Time: 9:30 PM EST
TV: Apple TV

The Galaxy has played 2 club friendlies this month. In the first, LA Galaxy fell to New York City FC 2-1. Then in the second, the Galaxy beat Toronto FC 2-1.

The Los Angeles Football Club starts their quest for the repeat without star Gareth Bale. No worries. LAFC has reloaded, which means that, once again, they’re the team to beat to win it all. The road L.A. team in this gets it done.

Soccer Pick: LAFC

Vancouver Whitecaps +136 vs. Real Salt Lake +200

When: Saturday, February 25
Where: BC Place, Vancouver

Time: 10:30 PM EST
TV: Apple TV, TSN, RDS

This should be one of the most competitive matches in MLS Week 1. Both teams had decent 2022 seasons.

Vancouver gets the edge because this happens on their pitch. But Real Salt Lake is good enough to at least get a draw. Both teams will be hesitant to push the attack too hard. A regulation tie seems probable.

Soccer Pick: Real Salt Lake

Seattle Sounders -118 vs. Colorado Rapids +310

When: Sunday, February 26
Where: BC Place, Vancouver

Time: 8:00 PM EST
TV: Apple TV, FS1

The Sounders show 3 losses and a couple of draws in their last 5. Seattle fell to Al Ahly at the FIFA Club World Cup on Feb. 4.

The loss was by a single goal. Colorado has drawn twice in their last 2 matches. The Rapids should play well. But Seattle gets home pitch advantage and, at least for now, looks like the better team.

Soccer Pick: Seattle Sounders