UEFA Champions League Betting Odds: Round of 16 Predictions

UEFA Champions League Betting Odds: Round of 16 Predictions

Written by on February 7, 2023

Champions League Round of 16 odds for first leg matches are set. AC Milan is the +146 chalk to take down Tottenham, Paris Saint-Germain is a +147 favorite versus Bayern and 2021 winner Real Madrid is an underdog in their first match versus Napoli.

Keep reading for Champions League odds and a preview of the Round of 16.


Champions League Round of 16 Odds to Advance to Quarterfinals

First Leg: Feb. 14 – Feb. 15 & Feb. 21 – Feb. 22

Second Leg: March 7 – March 8 & March 14 – March 15


First Leg Match Odds


AC Milan +146 vs. Tottenham +185

Tuesday, February 14th | Giuseppe Meazza, Milan, Italy
Milan has lost four straight heading into their Feb. 10 match versus Torino. Keep that in mind as you handicap this game.


Paris Saint-Germain +147 vs. Bayern Munich +156

Tuesday, February 14th | Parc des Princes, Paris, France
Without doing a deep dive, we’ll post a picks blog next week, the draw is enticing. PSG didn’t play well in the CL last season and although they’ve got a lot of stars, Bayern player Sadio Mane may step onto the pitch for this.


Borussia Dortmund +149 vs. Chelsea +172

Wednesday, February 15th | Signal Iduna Park, Dortmund, Germany
Chelsea is a solid club. However, Dortmund gets the Blues on their pitch. Not only that, but the Bundesliga team blasted Freiburg 5-1 on Feb. 4. So Dortmund is in great form.


Club Brugge +265 vs. Benfica -102

Wednesday, February 15th | Jan Breydelstadion, Bruges, Belgium
Brugge is a good team in their league. But the home dog doesn’t appear to have much shot versus a squad the quality of Benfica. Porto often makes it to the quarterfinals and Benfica has an 8-point lead over Porto in the Portuguese Liga.

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MyBookie Betting Lines for each Game


Second Leg Match Odds


Eintracht Frankfurt +186 vs. Napoli +135

Tuesday, February 21st | Deutsche Bank Park, Frankfurt, Germany
Napoli continues to dominate. On Jan. 13, Napoli dusted Juventus 5-1. In their latest on Feb. 5, Napoli beat Spezia 3-0.


Liverpool +125 vs. Real Madrid +196

Tuesday, February 21st | Anfield, Liverpool, Milan, Italy
As of Feb. 7, the Reds are 8-5-7-1 in the English Premier League. Because Pool is playing so poorly in the EPL, there’s a good chance they concentrate on the Champions League. El Blanco is the defending champs. So Liverpool isn’t a lock in the first leg.


Inter Milano -121 vs. FC Porto +320

Wednesday, February 22nd | Giuseppe Meazza, Liverpool, England
Inter is playing well. But before jumping on the home squad in the first leg, for sure check out Porto’s form. Yes, a lot can happen from now until Feb. 22.

However on Feb. 5, Porto won their fifth straight. So if the Liga squad maintains their excellent form leading into this, they for sure can pull off the upset win. Also, Porto always seems to step it up in Champions League matches.


RB Leipzig +320 vs. Manchester City -129

Wednesday, February 22nd | Red Bull Arena, Leipzig, Germany
Don’t decide which team to back until the week of. The problem with betting this early  is by doing so, you could end up on the wrong side.

The Sky Blues fell to Tottenham on Feb. 5. We know how talented Man City is, though. Also, Erling Haaland could step it up in this because he’s played against Leipzig before. On the flip side, Leipzig gets City on their grass. This is a wait for the right moment to bet match.

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MyBookie Betting Lines for each Game


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