With the 2018 March Madness producing some of the wildest results we’ve seen in quite some time, college basketball betting enthusiasts everywhere need to know what can be deemed as some ‘safe’ picks as we get set for the upcoming Sweet 16. Thankfully, I’ve got the bases covered with a trio of sweet, straight-up picks on three Sweet 16 matchups that all look like value-packed locks from where I’m sitting. Let’s get to them right now!
Not only that, but the Mountaineers’ pressure style won’t cause many turnovers against a Villanova team that is experienced enough to handle against anything you can throw at them. The Wildcats are playing some excellent basketball right now, having won seven straight games and nine of 10 while West Virginia has suffered a pair of losses to Kansas and one to Texas over their last 10 games. Villanova gets the hard-fought win in this one!
Pick: Villanova Wildcats 86 – West Virginia Mountaineers 81
2018 March Madness Sweet 16 Straight Up Betting Picks
No. 9 Kansas State Wildcats (24-11) vs. No. 5 Kentucky Wildcats (26-10)
- When: Thursday, March 22, 2018, 9:37 PM ET
- Where: Philips Arena, Atlanta, Georgia
- 2018 March Madness Sweet 16 Odds: Kentucky Wildcats -5.5 (Over/Under at 138.5)
No. 5 West Virginia Mountaineers (26-10) vs. No. 1 Villanova Wildcats (32-4)
- When: Friday, March 23, 2018, 7:27 PM ET
- Where: TD Garden, Boston, Massachusetts
- 2018 March Madness Sweet 16 Odds: Villanova Wildcats -5.5 (Over/Under at 154.5)

No. 3 Texas Tech Red Raiders (26-9) vs. No. 2 Purdue Boilermakers (30-6)
- When: Friday, March 23, 2018, 9:57 PM ET
- Where: TD Garden, Boston, Massachusetts
- 2018 March Madness Sweet 16 Odds: Purdue Boilermakers -1.5 (Over/Under at 137.5)