We are now just a pair of games away from knowing which two teams will be going head-to-head in the Champions League Final. The great news is that both Champions League Semi-Finals are still very much hanging in the balance after the opening leg, so it really is anyone’s guess as to who will be moving on.
With that in mind, let’s break down the betting for the Champions League semi-finals to help you select the wagers that are best for you.
Bet on the Champions League Semi-Finals Picks: Road to the 2025 Final
I think it’s fair to say that there have been some surprises to this point in the tournament, which has made Champions League betting a bit of a challenge this season.
As we head into Leg 2 of the tournament, it’s important to know where the matchups currently stand after the opening game, so let’s take a quick look.
Inter +186 vs Barcelona +117 (Draw +285)
Leg 1 was an absolute thriller, with Inter going on then road and getting a 3-3 draw against the tournament favorites.
PSG +106 vs Barcelona +228 (Draw +260)
It was a valuable 1-0 road win for PSG in Leg 1, but that will not be enough against a very strong Arsenal side.
^Best Champions League Bet to Make This Week
With both semi-finals so tight, can we really rely on Champions League betting trends?
There are several factors besides trends that come into play, such as recent form, injuries, and how the odds change with public perception and sharp action.
When making my Champions League Semi-Finals picks, I rely on all of those things, as well as the eye test from the opening game.
From what I have seen, I might be willing to play the underdog. Arsenal looks like a good double chance pick, as a road win or draw seems like a good option.
In the Inter/Barcelona game, I would be looking at playing the OVER on the total goals.
^Champions League Game Props: Top Props to Target
While the final result is the most important part of the game, Champions League game props are also fun to get in on.
There are several wagers on the goalscorer, such as first to score or anytime scorer.
There are also specific team Champions League prop bets, such as First team to Score and Win to Nil.
^Champions League Semi-Finals Picks provided by MyBookie
Champions League Final Odds: Who’s Favored After the Semis?
If you want to know how to bet on Champions League semi-final action, it’s good to look at the final 4 teams, the road they took to get there, and how things went in Leg 1.
With both matchups so close, the Champions League Final odds have not changed that much.
^Champions League Final Betting: Get Ahead of the Line Movement
Some of you are probably awaiting the end of the semi-finals before thinking about Champions League Final betting.
It’s not the worst idea, but the Champions League Final odds for each team remaining might be as good as they are going to get, so betting now may be the way to go.
^Conclusion: Bet Smart Before the Final Whistle
In the lead up to the Final, keep an eye on the changing odds so that your Champions League bets are as good as they can be.
The best way to keep an eye on the sportsbook odds is to create an account at MyBookie or to log into your existing account.
That is where you will find the most up-to-the-minute odds on the market.
^Who will reach the final?#UCL pic.twitter.com/ptO7637t1j
— UEFA Champions League (@ChampionsLeague) May 5, 2025
Champions League Semi-Finals Picks: Place your Bets anywhere, anytime by downloading the MyBookie APP |
Previous Betting News | MyBookie News Archive
Semifinals 2nd Leg Matches
In Champions League Semifinal first leg matches, Manchester City and Real Madrid drew and Inter dominated Serie A rival AC Milan.
Shortly after Inter’s demolition of Milan, oddsmakers set lines on the four semifinal participants to lift this season’s Champions League trophy.
See below for Champions League lines, analysis, and odds to win the 2nd leg of the semifinals.
Updated UEFA Champions League Odds to Win After the First Leg Semifinals | MyBookie Soccer Preview
Internazionale vs. AC Milan
When: Tuesday, May 16 at 3:00 pm ET
Where: Giuseppe Meazza, Milano, Italy
Inter had been rolling, which is why the 2-0 win over AC Milan doesn’t surprise. The match happened at Giusseppe Meazza. Neither team had an edge.
AC has no real shot of sticking with Inter. Milan is a good team, but Internazionale is better on all three levels, backline, midfield, and at the forward position.
Bet Inter vs. AC Milan Today
MyBookie Betting Lines for the Games
Real Madrid vs. Manchester City
When: Wednesday, May 17 at 3:00 pm ET
Where: Etihad Stadium, Manchester, England
El Blanco carried a 1-goal lead into the second half, but Man City kept at it. Kevin De Bruyne’s excellent shot at the sixty-seventh minute forced a 1-1 draw.
Real must now get by City at Etihad Stadium. That won’t be easy. The Sky Blues had the same strategy, at least getting a draw, in the first leg versus RB Leipzig. Then the Citizens blasted the Bundesliga rival 7-0 at Etihad.
Bet Real Madrid vs. Manchester City Today
MyBookie Betting Lines for the Games
Updated Champions League Final Picks
Top Pick: Internazionale +300
It’s going to be tough to beat Manchester City. However, the odds suggest City is unbeatable and that’s not the case.
Inter Milano is almost as loaded at the forward position as City. Romelu Lukaku and Lautaro Martinez are playing their best soccer of the season.
De Bruyne is the best mid in soccer. So we can’t argue that Man City has a better midfield than the Citizens. But Inter’s Nicolo Barella is very good.
Also, Cameroon goalie Andre Onana has hit his stride. He’s playing great soccer.
Will Inter beat Man City? Probably not. But at the odds, they’re worth taking a shot to get by the Sky Blues in the title game.
Second Pick: Manchester City -163
Real missed their chance. El Blanco had a goal lead against City. De Bruyne got the equalizer for the Citizens, which means if Real wishes to march to the Champions League Final, they must find a way to beat the Sky Blues at Etihad Stadium.
That could happen. It probably won’t. Pep Guardiola wanted at least a draw at Santiago Bernabeau. He got it. Now City’s skipper is going to unleash the full force of Manchester City’s attack onto Real.
Third Pick: Real Madrid +400
With that being written, if you don’t back Inter or Manchester City, Real is the only alternative left.
The good news is that El Blanco is good enough to beat Manchester City. The bad news is that it will be very difficult to do so at Etihad Stadium. But, again, if you don’t like Inter to win it all and you don’t want to accept Man City’s odds, backing Real is the only bet you’ve got.
Fourth Pick: AC Milan +2800
AC Milan should be a +5000 choice, not a +2800 pick. First, it will be close to impossible for Milan to break Inter’s excellent defense for a single goal much less 2.
Second, if AC Milan pulls off the miracle, they have to beat Manchester City or Real Madrid in the final match. The odds on AC make them an underlay to win it all.
Updated UEFA Champions League Odds to Win
- Manchester City -150
- Internazionale +300
- Real Madrid +400
- AC Milan +2800
Bet Champions League Semi-Finals Today
MyBookie Betting Lines for the Games
UEFA Champions League Semifinal 2nd Leg Schedule
Date | Time (/ET) | Home | Away | TV Info | |
---|---|---|---|---|---|
Tuesday, May 16 | 3:00 PM | Internazionale | vs. | AC Milan | |
2nd Leg – Internazionale lead 2-0 on aggregate | |||||
Wednesday, May 17 | 3:00 PM | Manchester City | vs. | Real Madrid | |
2nd Leg – Tied on aggregate |
Bet UEFA Champions League Semifinal
MyBookie Betting Lines for the Games
I have read enough, I need to place my bet now. What to do?
Bet Champions League Semi-Finals Today
MyBookie Odds for the Games
Soccer Betting Center
Soccer Odds and Lines
World Cup Odds |
UCL Odds | UEL Odds |
EPL Odds | Serie A Odds |
Bundesliga Odds |
La Liga Odds | Ligue 1 Odds |
Soccer Must-Know
Premier League Predictions |
Champions League Predictions |
World Cup Predictions |
EURO Predictions |
Copa America Predictions |
Latest Soccer Betting Predictions:
- LaLiga Betting Breakdown: Odds, Picks & Title Race Bets to Make This Week
- Serie A Betting: Weekly Matchday Picks, Odds Movement & Top Value Plays
- UEFA Champions League Semi-Finals Picks: Best Bets, Game Props & Final Odd to Lock In This Week
- Betting Liga MX with MyBookie: Play-In and Quarterfinals Matchups Insights for the Clausura 2025
- Now that Liverpool have won… Let’s see MyBookie Premier League Top Matchweek 35 Games
- Who will reach the Final Game? Get your CONCACAF Champions Cup Odds for Leg 2 Semifinal Matchups
- Bet on Champions League Games: First Leg Semifinal Odds and Expert Insights