49ers vs. Vikings Pick: NFL Las Vegas Betting Line for Week 2

As the San Francisco 49ers travel to face the Minnesota Vikings in the 2024 NFL Week 2 showdown, analyzing the NFL Las Vegas betting line is crucial for making smart betting decisions. With the 49ers favored by -5 and a total set at 46.5 points, our expert analysis will help you navigate this exciting matchup and place your bets strategically.

49ers vs Vikings Pick for the 2024 NFL Week 2 Game
Unlock the Winning Edge: Expert Picks for 49ers vs. Vikings NFL Week 2 Showdown!

2024 NFL Season | 104th season of National League in the United States
Week 2: Thursday, September 12th – Monday, September 16th, 2024

Betting 2024 San Francisco 49ers at Minnesota Vikings Week 2 Game

In what should be an excellent National Football League affair, the San Francisco 49ers are on the road at the Minnesota Vikings on Sunday.

This is part of Week Two in the National Football League.

Both teams come into the game with a 1-0 record on the season.

The 49ers are the defending NFC Champions, who lost in overtime to the Kansas City Chiefs a season ago.

The 49ers smacked the New York Jets on Monday Night Football to start the season.

For the Minnesota Vikings, despite being projected at the bottom of the NFC North, they dominated their Week One win.

The Vikings beat up the New York Giants and allowed just six points in the game.

The San Francisco 49ers are -5 on the road at the Vikings.

The total in this affair is 46.5 points.

NFL TNF Week 1: San Francisco 49ers at Minnesota Vikings
Sunday, September 15th, 2024 at 1:00 PM CBS | U.S. Bank Stadium, Minneapolis, MN

ATS Odds: San Francisco -5
Money line Odds: 49ers -232 / Vikings +184
Over/Under Odds: 46.5

Writer’s Breakdown and Pick for the 49ers vs Vikings Game

Road 49ers as Favorite to Win

Brock Purdy continues to put together solid performances under center for the 49ers.

The signal-caller tossed for 231 yards but did not score a touchdown in the win.

His top target was Jajaun Jennings with 64 receiving yards.

Jordan Mason was the big key in the game.

Christian McCaffrey was ruled out before the game, and Mason came in and rushed for 147 yards and a touchdown.

McCaffrey is doubtful to play in this game as well.

San Francisco will play back-to-back road games.

Next week, the 49ers will play their first divisional game of the season, as they are on the road at the Los Angeles Rams.

In Week Four, the 49ers will host the Patriots.

Vikings Seeking 2-0 Start

Kevin O’Connell had his group ready to go in the season-opening win at the New York Giants.

The Vikings saw Sam Darnold pass for 207 yards and two touchdowns in the game.

He also threw an interception in the game.

He is starting due to the loss of rookie JJ McCarthy to injury.

Star Justin Jefferson led the team in receiving, but he was held to just 59 yards in the game.

He scored one of the touchdowns, and Jalen Nalor scored the other.

New running back Aaron Jones was strong in the game as well.

He rushed 14 times for 94 yards and a touchdown.

Minnesota will host the Houston Texans in Week Three.

In Week Four, the Vikings play their first divisional game of the season.

Minnesota is on the road at Green Bay.

The final game before their bye is Week 5 in London against the Jets.

Competitive Game

This is going to be an interesting football game.

The 49ers have a short week.

San Francisco has a long trip for this game.

The 49ers have to play in a different time zone.

San Francisco is coming off an emotional win.

The crowd will be pumped for this game.

We expect Minnesota to be prepared for this game.

Ultimately, the 49ers win the game, but Minnesota covers this spread.

Take the Minnesota Vikings +5 over the San Francisco 49ers in NFL action on Sunday.

San Francisco at Minnesota Betting Trends Today

49ers’ record against the spread last year was 9-7-1.
49ers had an ATS record of 5-6-1 as 5.5-point favorites or more last season.
In 17 49ers games last year, nine went over the total.
Vikings’ record against the spread last season was 7-7-3.
Vikings won once ATS (1-0-1) as underdogs of 5.5 points or more last year.
There were seven Vikings games (out of 17) that hit the over last year.
Minnesota went 2-6 at home last season.
Minnesota rushing offence was ranked 18th in the league in week 1.
San Francisco are ranked 2nd in opposition rushing yards allowing just 68yds in week 1.
Deebo Samuel had 23 rushing yards 54 receiving yards and a touchdown in week 1.
Total has gone UNDER in 4 of San Francisco’s last 5 games against an opponent in the National Football Conference North division.
Total has gone UNDER in 6 of Minnesota’s last 8 games played in September.

Vikings vs. 49ers Series History

Last meeting:
49ers 17, Vikings 22 on October 23rd, 2023: Regular Season Match – U.S. Bank Stadium, Minneapolis, MN

Head-to-head (includes postseason games):
San Francisco 49ers lead series 25-24-1

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Vikings safety Harrison Smith missed today's practice due to a hip injury

His status for Sunday vs. the 49ers is unknown pic.twitter.com/51tcw8vaAx
— The Viking Age (@TheVikingAge) September 12, 2024