Buffalo vs Detroit Odds: Matchup Looks Like O/U Lock Alert!

The Buffalo Bills and Detroit Lions will both look to close out the preseason with a win after falling in their respective Week 3 preseason matchups. The two playoff hopeful teams will square off on Thursday night at Ford Field.

Now, let’s find out who’s getting the ATS win! Get the updated online NFL betting odds here.

Bills Vs Lions Matchup Looks Like O/U Lock Alert!

When: Thursday, September 1, 2016 at 7:30 PM ET
Where: Ford Field
NFL Odds: Detroit Lions -3 / Over/Under: 38.5

Why Bet Buffalo +3 Points

The Buffalo Bills were on the wrong end of a humbling 21-16 loss against the Washington Redskins in Week 3. Backup quarterback EJ Manuel passed for 221 yards and one interception while Walter Powell and Daniel Herron combined for 104 receiving yards on 10 catches. Jonathan Williams rushed for a team-high 42 yards and one touchdown while Robert Blanton led the Bills with four tackles.

Why Bet Detroit -3 Points

The Detroit Lions got smacked around in their 30-9 Week 3 loss against Baltimore. Starting quarterback Matthew Stafford passed for 95 yards and one interception while TJ Jones and Golden Tate combined for 58 receiving yards on four catches. Theo Riddick rushed for a team-high 35 yards on three carries while Antwione Williams recorded a team-high six tackles and Haloti Ngata added one sack.

Expert Prediction and Betting Pick

I haven’t seen a single thing out of either one of these teams that makes me think there’s going to be any competent defense being played. Having said that, I think the best play for this matchup is a pick for the Over 38.5 total points. Both, E.J. Manuel and Dan Orlovsky are pretty decent quarterbacks that could likely start for a handful of teams leading me to believe both veteran backups will put up their fair share of points. Play the Over!