Colts vs Cardinals Betting Preview - NFL Week 16 Odds

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While most of us will be recovering from eating too much at Christmas dinner, there will be four teams playing football on Christmas Day. There are two games set to go on the 25^th, both of which have massive playoff implications. We are jumping ahead to the night game, which will see the Indianapolis Colts hitting the road to face the Arizona Cardinals. There is an expectation that both of these teams will still be playing football beyond the end of the regular season, but there is still a lot that can change over the final 3 weeks of the season. While the Colts are surging, the Cardinals are slipping, so who knows what to expect here. The Cardinals are a 1-point home favorite, with the point total set at 49. That being said, let’s take a look at our NFL Betting preview for the upcoming match between the Colts and Cardinals.

NFL Betting Analysis for Indianapolis Colts at Arizona

How to Bet On Indianapolis Colts vs Arizona Cardinals & TV Info

When: Saturday, December 25 at 8:15 PM EST
Where: State Farm Stadium, Glendale
TV: NFL TV
Total: Over 49 (-110) / Under 49 (-110)
Spread: PK -110

Why bet on the Indianapolis Colts

The Indianapolis Colts might well be getting hot at the right time of the season, as they come into this one having won 2 in a row and 5 of their last 6 games. Their only loss during that stretch came at the hands of the Super Bowl champion Tampa Bay Buccaneers in a game that really could have gone anyway. The Colts have the #5 seed at the moment, but they are also within reach of the Tennessee Titans at the top of the division. They could put the pressure on in a big way with another win here. The Colts have been a great pick against the spread, going 8-3 ATS in their last 11 games. They have also covered the spread in each of their last 5 road games. The OVER has hit in 5 of their last 6 non-conference games.

Why bet on the Arizona Cardinals

The Cardinals came into the season as a bit of a dark horse, but they quickly became a favorite after they started racking up wins. There are some fans and pundits who fear that this team is in danger of going into a late season slump. They have lost 2 in a row ahead of this one, including a stunning 30-12 loss to the Detroit Lions last weekend. You have to wonder if this is a minor blip on the radar or a sign of a bigger issue. In fairness to the Cardinals, they have had some big injury issues to deal with. This is still a team that has won 10 of their last 14, plus they are also 8-4 ATS in their last 12. What may come as a bit of a surprise is that they are just 3-8 ATS in their last 11 home games. This is a matchup that has seen the UNDER hit in 6 of the last 7 games.

Expert Pick and Final Score Prediction

This is a huge game in terms of the standings in both conferences, and I expect this to be a close game. I tend to go with teams that are one a roll, which is why I am leaning towards the Indianapolis Colts getting the big win on the road.

NFL Week 16 Betting Pick: Indianapolis Colts 27 Arizona Cardinals 24

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