49ers vs Patriots Odds: Week 4 Game Prediction

Two of the most successful franchises in Super Bowl history meet on Sunday but both with 1–2 records as the New England Patriots visit the injury-ravaged San Francisco 49ers, who are solid favorites on the NFL odds.

New England Patriots

At some point this year, Maye is taking over, but first-year coach Jerod Mayo is sticking with Brissett for now. He’s completed 60.9 percent of his passes for 368 yards and a touchdown. Jacoby has been the ultimate professional throughout this process. He knows he’s New England’s placeholder quarterback.

Jacoby Brissett

Through three weeks, Jacoby has been sacked nine times. Only eight quarterbacks have been sacked more. His sack percentage (times sacked when a quarterback attempts a pass) is the third highest in the NFL at 11.54%. Last week, against the Jets, he was sacked 21.74% of the time when he dropped back to pass. The Patriots have allowed a worse sack percentage just once since 2000 – when Tom Brady was sacked 25% of the time in a 2001 win over Buffalo.

The potential return of starting left guard Sidy Sow (ankle) this week is one silver lining for a unit that is holding the team back.

“We’ve had a formula we’ve tried to play, and I thought we did a good job of that the first two weeks,” center and longtime captain David Andrews said after the Jets loss. “This wasn’t it.”

New England played without four-time team captain, linebacker and 2023 leading tackler Ja’Whuan Bentley in Week 3, and he was placed on IR this week with a pectoral injury and could miss the rest of the season with his earliest possible return coming in Week 8 when the Patriots play the Jets.

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Patriots vs 49ers Odds provided by MyBookie Sportsbook

San Francisco 49ers

Jauan Jennings

He became the fourth player in franchise history to have 175 receiving yards and three scores in the same game. The TDs were more than Jennings had the past two seasons combined, and were the most TDs by a 49ers receiver since Terrell Owens in Week 5, 2001. Jennings’ previous career high in receiving yards was a mere 94 yards.

Injuries

It’s possible that Kittle plays this week, but Samuel and McCaffrey remain out. McCaffrey, the 2023 NFL Offensive Player of the Year, recently flew to Germany to see a specialist about the Achilles tendonitis that had landed him on IR.

“It’s a big [loss],” coach Kyle Shanahan said of Hargrave. “I thought he had his best game (vs. the Rams). I thought he was a huge factor, really affected the quarterback in that game. … He’s one of our better players. He was definitely going in the right direction and was going to have a big year.”

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