As best NFL bets today take center stage in Week 12, NFL fans are treated to some thrilling quarterback matchups, with huge duels like Bryce Purdy leading the 49ers to Lambeau Field to face Jordan Love and the Packers. In addition, Jalen Hurts and the Eagles take on Matthew Stafford and the Rams, while Justin Herbert and the Chargers host Lamar Jackson and the Ravens—making this a must-watch weekend for NFL bettors.
2024 NFL Week 12 Quarterback Matchups
Week 12 QB Showdown: Who Will Reign Supreme?
2024 NFL season | 104th season of National Football League in the United States
Week 12: Thursday, November 21st – Monday, November 25th, 2024
Betting Week 12 NFL Games
Huge NFL QB duels dot the week 12 schedule.
Perhaps, none is bigger than Bryce Purdy leading the 49ers to Lambeau Field to take on Jordan Love and the Packers.
Both Green Bay and San Francisco are fighting for playoff spots.
Also in NFL Week 12, Jalen Hurts and the high flying Eagles head to SoFi to take on Matthew Stafford and the Rams and Justin Herbert and the Bolts host Lamar Jackson and the Ravens.
Check out analysis and picks for NFL Week 12’s top quarterback matchups.
Writer’s NFL Quarterback Picks for the Week 12 Matchups
Pittsburgh – Russell Wilson at Cleveland – Jameis Winston
Thursday, November 21st, 2024
When Winston is on, he can light up the scoreboard.
The former Heisman Trophy winner continues to have a cannon for an arm.
But Winston has always been a gambler.
That will backfire on Thursday versus the stout Pittsburgh D.
Russell Wilson has been electric since taking over the playoff bound Steelers.
The Pittsburgh offense has gotten into a rhythm.
Russ wins this battle.
NFL Week 12 QB Pick: Russell Wilson
Minnesota – Sam Darnold at Chicago – Caleb Williams
Sunday, November 24th, 2024
Caleb Williams and the Bears started the season 4-2 but since then the wheels have fallen off the wagon.
After completing over 79% of his passes versus the Jags, Caleb completed less than 42% in a loss to the Commanders and less than 54% in losses to the Cardinals and Patriots.
Sam Darnold is no longer an MVP candidate like he was earlier in the season.
But Darnold will play enough to outduel Williams in this.
Back Darnold in any head to head betting option.
NFL Week 12 QB Pick: Sam Darnold
San Francisco – Bryce Purdy at Green Bay – Jordan Love
Sunday, November 24th, 2024
Purdy versus Love should be a terrific matchup.
Two of the youngest starting quarterbacks in the league have plenty of weapons that will help them thrive in this game.
Love has the advantage because this happens at Lambeau.
Also, Jordan doesn’t have a running back like Christian McCaffrey on which to lean.
The 49ers should leave Green Bay with a victory but Love will post the better stats.
NFL Week 12 QB Pick: Jordan Love
Arizona – Kyler Murray at Seattle – Geno Smith
Sunday, November 24th, 2024
If the playoffs started today, the NFC West division winner would be the Arizona Cardinals.
Projected as one of this season’s worst teams.
The reason AZ is a playoff contender, and, maybe, even a conference contender is because of Kyler Murray.
The diminutive QB is showing he’s got a lot of great football left.
Murray has single handedly taken over games this NFL season ala Lamar Jackson.
Smith could get roughed up by a solid Arizona defense.
Murray wins the matchup.
NFL Week 12 QB Pick: Kyler Murray
Philadelphia – Jalen Hurts at LAR – Matthew Stafford
Sunday, November 24th, 2024
Hurts and the Eagles are on fire.
Since a loss to the Buccaneers in NFL Week 4, Hurts and the Eagles have won 6 straight.
No victory was as important as the NFL Week 11 victory over Philly’s top competition for the NFC East title, the Washington Commanders.
The Philadelphia D held Jayden Daniels and the Commanders to 18 points.
Stafford and the Rams will struggle to keep pace.
Jalen gets it done.
NFL Week 12 QB Pick: Jalen Hurts
Monday, November 25
Baltimore – Lamar Jackson at LAC – Justin Herbert
Monday, November 25th, 2024
Lamar Jackson versus Justin Herbert should be an interesting quarterback matchup but the styles that the two teams play ensures Lamar wins the QB battle.
Jackson must have a good game in this one for Baltimore to get the W.
The Bolts boast a terrific run defense.
No doubt Derrick Henry will have a decent game.
But DH won’t take over the game.
Herbert and the Chargers run a methodical offense that keeps the ball in their hands.
Jackson wins the battle but don’t be surprised if the Bolts pull off the home upset victory.
NFL Week 12 QB Pick: LA Chargers
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^ Top^ Top“Geno Smith is your quarterback 😂” pic.twitter.com/HZ1fcVjflC
— le spoon (@FDT4EVUR) November 18, 2024
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2025 NFL Conference Championship
See who clashes in the opening act of the NFL season with this Conference Championship game schedule.
| Matchup | Time | TV | Location | |
|---|---|---|---|---|
| Sunday, February 9, 2025 | ||||
| Super Bowl Sunday | ||||
| Kansas City | @ Philadelphia | 6:30 PM | FOX | Caesars Superdome, New Orleans, LA |
| Betting Lines for NFL Games | Conference Championship Games of the NFL Season | ||||
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