NFL Week 12 Odds: Quarterback Matchups and Bets Today

As best NFL bets today take center stage in Week 12, NFL fans are treated to some thrilling quarterback matchups, with huge duels like Bryce Purdy leading the 49ers to Lambeau Field to face Jordan Love and the Packers. In addition, Jalen Hurts and the Eagles take on Matthew Stafford and the Rams, while Justin Herbert and the Chargers host Lamar Jackson and the Ravens—making this a must-watch weekend for NFL bettors.

2024 NFL Week 12 Quarterback Matchups
Week 12 QB Showdown: Who Will Reign Supreme?

2024 NFL season | 104th season of National Football League in the United States
Week 12: Thursday, November 21st – Monday, November 25th, 2024

Betting Week 12 NFL Games

Huge NFL QB duels dot the week 12 schedule.

Perhaps, none is bigger than Bryce Purdy leading the 49ers to Lambeau Field to take on Jordan Love and the Packers.

Both Green Bay and San Francisco are fighting for playoff spots.

Also in NFL Week 12, Jalen Hurts and the high flying Eagles head to SoFi to take on Matthew Stafford and the Rams and Justin Herbert and the Bolts host Lamar Jackson and the Ravens.

Check out analysis and picks for NFL Week 12’s top quarterback matchups.

Writer’s NFL Quarterback Picks for the Week 12 Matchups

Pittsburgh – Russell Wilson at Cleveland – Jameis Winston

Thursday, November 21st, 2024

When Winston is on, he can light up the scoreboard.

The former Heisman Trophy winner continues to have a cannon for an arm.

But Winston has always been a gambler.

That will backfire on Thursday versus the stout Pittsburgh D.

Russell Wilson has been electric since taking over the playoff bound Steelers.

The Pittsburgh offense has gotten into a rhythm.

Russ wins this battle.

NFL Week 12 QB Pick: Russell Wilson

Minnesota – Sam Darnold at Chicago – Caleb Williams

Sunday, November 24th, 2024

Caleb Williams and the Bears started the season 4-2 but since then the wheels have fallen off the wagon.

After completing over 79% of his passes versus the Jags, Caleb completed less than 42% in a loss to the Commanders and less than 54% in losses to the Cardinals and Patriots.

Sam Darnold is no longer an MVP candidate like he was earlier in the season.

But Darnold will play enough to outduel Williams in this.

Back Darnold in any head to head betting option.

NFL Week 12 QB Pick: Sam Darnold

San Francisco – Bryce Purdy at Green Bay – Jordan Love

Sunday, November 24th, 2024

Purdy versus Love should be a terrific matchup.

Two of the youngest starting quarterbacks in the league have plenty of weapons that will help them thrive in this game.

Love has the advantage because this happens at Lambeau.

Also, Jordan doesn’t have a running back like Christian McCaffrey on which to lean.

The 49ers should leave Green Bay with a victory but Love will post the better stats.

NFL Week 12 QB Pick: Jordan Love

Arizona – Kyler Murray at Seattle – Geno Smith

Sunday, November 24th, 2024

If the playoffs started today, the NFC West division winner would be the Arizona Cardinals.

Projected as one of this season’s worst teams.

The reason AZ is a playoff contender, and, maybe, even a conference contender is because of Kyler Murray.

The diminutive QB is showing he’s got a lot of great football left.

Murray has single handedly taken over games this NFL season ala Lamar Jackson.

Smith could get roughed up by a solid Arizona defense.

Murray wins the matchup.

NFL Week 12 QB Pick: Kyler Murray

Philadelphia – Jalen Hurts at LAR – Matthew Stafford

Sunday, November 24th, 2024

Hurts and the Eagles are on fire.

Since a loss to the Buccaneers in NFL Week 4, Hurts and the Eagles have won 6 straight.

No victory was as important as the NFL Week 11 victory over Philly’s top competition for the NFC East title, the Washington Commanders.

The Philadelphia D held Jayden Daniels and the Commanders to 18 points.

Stafford and the Rams will struggle to keep pace.

Jalen gets it done.

NFL Week 12 QB Pick: Jalen Hurts

Monday, November 25

Baltimore – Lamar Jackson at LAC – Justin Herbert

Monday, November 25th, 2024

Lamar Jackson versus Justin Herbert should be an interesting quarterback matchup but the styles that the two teams play ensures Lamar wins the QB battle.

Jackson must have a good game in this one for Baltimore to get the W.

The Bolts boast a terrific run defense.

No doubt Derrick Henry will have a decent game.

But DH won’t take over the game.

Herbert and the Chargers run a methodical offense that keeps the ball in their hands.

Jackson wins the battle but don’t be surprised if the Bolts pull off the home upset victory.

NFL Week 12 QB Pick: LA Chargers

Bet the NFL Week 12 | NFL Live Betting MyBookie Betting Lines for the Tournament

^ Top