Indianapolis battles Buffalo in a game between teams with contrasting philosophies. The Bills rely on their defense while the Colts rely on their offense. Will Indianapolis score enough points to cover the spread against defensive-minded Buffalo? See below for our analysis, NFL odds, and a free pick when the Colts host the Bills!
Indianapolis quarterback Andrew Luck has already thrown 16 touchdowns this season. Luck, who didn’t play at all in 2017, has led Indianapolis to 24 points or more in 3 straight. Colts scored 34 against Houston, 24 against New England, and 34 against the Jets.Sure, Indianapolis failed to win any of the 3 straight up or against the spread, but all 3 opponents have decent enough offenses to score with the Colts. The Bills don’t.
Bills at Colts NFL Week 7 Lines & Betting Analysis
What do you think of the odds for next week’s game? #BUFvsIND https://t.co/CP6hHPKn7K
— Buffalo Bills News (@billsupdates) October 15, 2018
- When: Sunday, Oct. 21 at 1:00 pm ET
- Where: Lucas Oil Field, Indianapolis, IN
- TV: CBS
- Radio: Buffalo / Indianapolis
- Live Stream: NFL Live
- ATS Odds: Indianapolis -7.5 (-110)
- Over/Under Total Odds: 43.5 (-110)
Weather Forecast
- Clear: 8°C/47°F
- Humidity: 49%
- Precipitation: 0%
- Wind: 8 mph NW
- Cloud Cover: 5%
- Type of Stadium: Retractable
Why Buffalo Bills are a good bet at +7.5?
Buffalo’s only 2-2 straight up in their last 4. They’re 3-1 against the spread in their last 4, though. Buffalo’s been underappreciated this entire year. They pulled off the amazing moneyline win over Minnesota as a huge +17 dog. They covered in Week 6 in a loss to Houston and they covered when losing by a single point to Tennessee in Week 5.Bills play good enough defense to keep the Colts within a TD and extra point. Leaning on their defense, Buffalo might not win the game, but they can cover the spread.Team Statistics
Offense:- Average Score For: 12.7
- Total Yards: 222.5
- Pass Yards: 123
- Rush Yards: 99.5
- Average Score Against: 23
- Total Yards: 311.7
- Pass Yards: 219.2
- Rush Yards: 92.5
Why Indianapolis Colts are a good bet at -7.5?

Team Statistics
Offense:- Average Score For: 25.3
- Total Yards: 369.2
- Pass Yards: 286
- Rush Yards:83.2
- Average Score Against: 30
- Total Yards: 386.8
- Pass Yards: 280
- Rush Yards: 106.8
Bills at Colts NFL Week 7 Betting Trends
- Buffalo is 4-2 ATS in the last 6 games on the road
- Buffalo is 2-5 SU in the last 7 games
- The total went UNDER in 4 of Buffalo’s last 5 games
- Indianapolis is 2-4 ATS in the last 6 games
- Indianapolis is 2-11 SU in the last 13 games
- The total went OVER in 4 of Indianapolis’s last 6 games