Top 2022 NFL Week 4 Games to Wager On: TNF, SNF, and MNF Betting Picks

Top 2022 NFL Week 4 Games to Wager On: TNF, SNF, and MNF Betting Picks

On Thursday, Miami and Cincinnati kick off what promises to be an exciting NFL Week 4. Other top matchups include Jacksonville throwing down against the Eagles, the Ravens hosting the Bills and the Buccaneers taking on the Chiefs. Keep reading for a NFL Betting rundown of the TNF, SNF, MNF, and top 1 pm and 4 pm games happening in NFL Week 4. 

NFL Week 4 Betting Rundown for the Best TNF, SNF, MNF Games of the 2022-23 Season

2022 NFL Week 4

  • When: Thursday, Sep. 29 – Monday, Oct. 3

Miami Dolphins at Cincinnati Bengals -3.5 | Thursday, Sep. 29

If Tua plays, and right now he’s not even listed as questionable, the Bengals should be in some trouble. Joe Burrow is going to have a heck of a time against Miami’s defense. 

Tagovailoa should burn Cincinnati’s secondary. Tua and the Fins go to 4-0. 

NFL Week 4 Pick: Miami Dolphins +3.5 

Jacksonville Jaguars at Philadelphia Eagles -6.5 | Sunday, Oct. 2

The Eagles have become the NFC’s top choice to win Super Bowl 57. Philadelphia offers lower odds than the Tampa Bay Buccaneers, Green Bay Packers, and Los Angeles Rams.

But although Philly is a good team, the Jaguars have won back-to-back games versus teams many expected would blow them out, the Colts and the Chargers. 

The Eagles wins were against Detroit, Philadelphia required overtime to beat the Lions, Minnesota, and Washington. The Jags can win this straight up. 

NFL Week 4 Pick: Jacksonville Jaguars +6.5

Los Angeles Chargers -5.5 at Houston Texans | Sunday, Oct. 2

Chargers’ quarterback Justin Herbert is banged up and the offensive line must play the entire season without left tackle Rashawn Slater. Houston is 2-0-1 against the spread in 3 games. Texans cover.  

NFL Week 4 Pick: Houston Texans +5.5 

Washington Commanders at Dallas Cowboys -3 | Sunday, Oct. 2

Washington can score, but the Commanders appear to have already given up on the season. D.C. did nothing versus a division rival in week 3, falling to the Eagles by a 24-8 score. 

Dallas backup Cooper Rush made it 3-0 after the Cowboys beat the Giants at the Meadowlands on Monday night. Dallas is the much better team. Yes, this is a rivalry game, but the Boys should rock the Commanders. 

NFL Week 4 Pick: Dallas Cowboys -3 

Buffalo Bills -3.5 at Baltimore Ravens | Sunday, Oct. 2

No doubt this is one of the most intriguing games in NFL Week 4. Baltimore is the highest scoring team in the NFL, averaging over 33 points per game.

Buffalo lost to division rival Miami in week 3, which means a bounce back could be in order. But Buffalo has some key injuries on defense. The Ravens are the play. 

NFL Week 4 Pick: Baltimore Ravens +3.5 

New England Patriots at Green Bay Packers -10.5 | Sunday, Oct. 2

Patriots starting quarterback Mac Jones is out for a while. That’s bad news for New England and their fans because Aaron Rodgers and the Packers head into this after beating Brady and the Buccaneers 14-12.

10.5 points is a lot. But New England should have trouble getting 3 against Green Bay at Lambeau. Laying the points makes sense.  

NFL Week 4 Pick: Green Bay Packers -10.5  

NFL Sunday Night Football: Kansas City Chiefs -2.5 at Tampa Bay Buccaneers | Sunday, Oct. 2

Tampa is playing great on defense. But the offense is struggling, which explains why Kansas City is a -2.5 chalk. 

If Tom Brady and offense step up, the Buccaneers can win this but it’s tough to have faith in Brady and his mates. KC is the play. 

NFL Week 4 Pick: Kansas City Chiefs  

Los Angeles Rams at San Francisco 49ers -2.5 | Monday, Oct. 3

San Francisco’s defense should have no trouble containing Matthew Stafford and the Rams offense. Not only that, but the Rams have injuries in their secondary.

Jimmy Garoppolo, Deebo Samuel, and the Niners offense should put up enough points to cover the spread. San Francisco gets the nod in NFL Week 4’s Monday night matchup. 

NFL Week 4 Pick: San Francisco 49ers -2.5


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