NFL Week 15 Lines & Predictions: This Week's Betting Winners

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After Week 14, we move on to Week 15, where clubs are vying for a postseason spot as we head into mid-December action. We’ll predict who we believe to be the Week 15 sure winners on MyBookie. We’ll examine these matchups in more detail and offer you our top NFL Betting predictions for the following week.

Who Are the Sure Winners in Week 15 of NFL Action?

San Francisco 49ers (-3.5) vs Seattle Seahawks

We kick this week off with a Thursday night football matchup between the 49ers and the Seahawks. After opening up as -1 point favorites, the 49ers have quickly jumped to -3.5 point favorites (-110) on mybookie. Questions surrounded the San Francisco offensive unit After Jimmy Garoppolo went down with a leg injury, however, Brock Purdy led the 49ers to a huge victory over the Tampa Bay Buccaneers as they posted 35 points and held the Bucs to just seven points.

Meanwhile, the Seattle Seahawks have struggled in their last four games. Seattle surrendered 30 points to the Carolina Panthers last week in a disappointing loss and have now lost three of the last four contests. Seattle is conceding 28.5 points over their last four games and have failed to cover the spread in each of those games. Except for the 49ers, they have a huge day against the Seahawks.

Indianapolis Colts vs Minnesota Vikings (-4.5)

The Minnesota Vikings are primed to crush the Colts in their upcoming matchup for Week 15. Despite losing last week, the Viking offense is one of the most dominant forces in the league. Kevin O’Connel’s group is averaging 24 points and over 340 yards per game. They also have a lot more to play for as the Vikings look to secure the number one overall seed in the NFC playoffs.

Indianapolis, on the other hand, were embarrassed by the Cowboys 54-19 on the road in their last time out. Additionally, they have lost five of their last six contests and are 2-5 ATS over their last seven contests. Nothing seems to be going right in Indy; the offense owns the most giveaways in the league (26), while their defense is tied for 30th in takeaways (12). Count on the Vikings to pummel the Colts at home in Week 15.

Cincinnati Bengals (-3) vs Tampa Bay Buccaneers

Lock in the Bengals as sure winners heading into their Week 15 matchup against the Tampa Bay Buccaneers. The Cincinnati Bengals took care of business against the Browns last week, winning 23-10 and pushing their winning streak to five games. Cincinnati is one of the hottest teams in football, as the Bengals have covered the spread ten times over their last 11 games. The Bengals got Ja’Marr Chase back, and Joe Burrow continued to sling the football as he collected his 25th touchdown pass in the win over Cleveland.

The Tampa Bay Buccaneers are leading the NFC South however, they now fall below .500 (6-7) on the year after they were crushed by the 49ers last week 35-7. Tom Brady and the Buccaneers are clearly not close to the Super Bowl champs they once were two years ago. Tampa has covered the spread just once in their last ten contests, while the offense has managed only 13.7 points over their last three games.

The Bengals will be sure-fire winners come Week 15.