NFL 2021 Season Week 15 O/U Betting Picks, Odds & Predictions

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We are at the stage of the NFL season where you need to start paying attention to game times. The league is shifting games around via their flex schedule and now also have Saturday games on the calendar. We actually have a couple of games set to go on Saturday in Week 15, which is great for fans, but tough for bettors if you have what you believe to be a hot pick but go to place it on the wrong day. We have one of the Saturday games on our O/U picks for the week as we look to repeat our parlay from last weekend. As always, we have selected 3 games to bet against the NFL Odds that we like in terms of the point total, so let’s go ahead and break those down.

2021 Season Week 15 Over/Under Picks | NFL Betting

New England Patriots at Indianapolis Colts (OVER 45 ½)

One of the things that makes this game so interesting is that these are two teams that could potentially meet in the playoffs. Right now, the Patriots are in as the #1 seed, but with things so tight at the top, there is no guarantee that they will still be there once the season comes to a close. The Colts are currently sitting in the #6 spot in the AFC and are a couple of wins back of the Titans in the AFC South. Making that up with 4 games remaining is not going to be easy, but a win here would help. The Patriots have seen the OVER hit in 6 of their last 9 games, while the OVER has hit for the Colts in 5 of their last 7. I think they get beyond that 45 ½ point total quite easily.

Dallas Cowboys at New York Giants (OVER 44 ½)

It has been a bit of an up and down season for the Dallas Cowboys, but with just 4 weeks left on the season, they look to be a lock to win the NFC East. They have an opportunity to drive that home this weekend when they head to the Big Apple to face the New York Giants. Dallas has won back-to-back games, including a huge win over Washington last week, and will be looking to keep it rolling. The Giants have lost 2 in a row and are struggling on the offensive side of the football, which does make taking the OVER seem a bit risky. While both of these teams have been trending under over the past few weeks, it is worth noting that the OVER has hit in 5 of the last 6 head-to-head matchups between these two.

Tennessee Titans at Pittsburgh Steelers (OVER 41 ½)

Through last season and the first half of this year, the Steelers defense was arguably among the best in the league. They have gone off the rails in the past few weeks now and are routinely getting lit up by the opposition. Despite all of that, the Steelers are 6-6-1 and still in with a shot at making the playoffs, but they are at the point where there is zero margin for error. The Titans are on the brink of locking up the AFC South and getting a good seed in the playoffs, but this trip is still a tricky one. Tennessee tends to see the scores go up on the road, with 6 of their last 7 away from home going OVER. Furthermore, 12 of the last 18 meetings between these two teams have gone OVER.

I have read enough, I need to place my bet now. What to do?