NFL Week 15 Straight Up Betting Picks & Odds: Best Games to Wager On

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The top straight up plays in NFL Week 15 happen on Sunday starting with the Detroit Lions versus the New York Jets and ends on Monday with the Rams at Lambeau taking on Aaron Rodgers and the Packers. See below for NFL Lines and SU picks for eight of this week’s top NFL matchups.

SU Picks For This Weekend’s NFL Games | Week 15 Betting Lines and Predictions

Detroit Lions -111 vs New York Jets -109 | Sunday, Dec. 18

The odds suggest the Lions have the edge, but the Jets play Detroit on their field. It should be mighty cold and Detroit has yet to face a defense as solid as NYJ’s.

New York gets a reprieve of sorts after having had to face Buffalo’s defense in their last. The Jets get the nod.

NFL Week 15 Pick: New York Jets -109

Dallas Cowboys -232 vs. Jacksonville Jaguars +185 | Sunday, Dec. 18

Dallas struggled versus a tough Houston Texans squad in week 14. The Cowboys almost lost, which would have caused mass hysteria because the Boys entered the game a -17 chalk.

Jacksonville dusted Tennessee 36-22 in their last. Jaguars’ quarterback Trevor Lawrence has hit his stride and the Jaguars face the Boys on their field. Jacksonville is the play.

NFL Week 15 Pick: Jacksonville Jaguars +185

Pittsburgh Steelers +115 vs. Carolina Panthers -141 | Sunday, Dec. 18

Carolina is rolling. The Panthers have won 3-of-4. Not only that, but Carolina hosts Pittsburgh a week after rushing for 223 yards against Seattle in a road upset victory.

Pittsburgh is going to have a tough time stopping the Panthers rushing attack. Also, the Steelers may have start Mitch Trubisky at quarterback and that wouldn’t be good.

NFL Week 15 Pick: Carolina Panthers -141

New England Patriots -118 vs. Las Vegas Raiders -118 | Sunday, Dec. 18

Raiders versus Patriots projects as a terrific game. The problem Vegas has in the contest is that their head coach, Josh McDaniels, learned under the master of all coaches, Bill Belichick.

Bill knows Josh’s playing calling tendencies. It’s going to be difficult for the Raiders to pocket a win on Sunday.

NFL Week 15 Pick: New England Patriots -118

Tennessee Titans +129 vs. Los Angeles Chargers -158 | Sunday, Dec. 18

The Titans have injuries along their offense line, which means Derrick Henry won’t be as effective as he would normally be versus the Chargers’ porous rush defense.

Tennessee also has issues in the secondary, which means Justin Herbert should light it up. Bolts win their second straight.

NFL Week 15 Pick: Los Angeles Chargers -158

Cincinnati Bengals -158 vs. Tampa Bay Buccaneers +160 | Sunday, Dec. 18

Tampa’s D really struggled in week 14, giving up 35 points to rookie Brock Purdy and the San Francisco 49ers.

The Bengals went about their business winning their fifth straight. Cincinnati has won 8-of-10 and are starting to resemble the squad that made it to the Super Bowl last season.

NFL Week 15 Pick: Cincinnati Bengals -158

New York Giants +183 vs. Washington Commanders -129 | Sunday, Dec. 18

This is a tough game. But there isn’t enough difference in odds to side with the Giants. NYG heads into this after a 48-22 spanking from the Philadelphia Eagles.

The Commanders host NYG after their bye. These two played to a 20-20 tie in the first head-to-head. Don’t expect another tie because this happens on FedEx Field in D.C.

NFL Week 15 Pick: Washington Commanders -129

Los Angeles Rams +265 vs Green Bay Packers -349 | Monday, Dec. 19

The Packers could have trouble moving the football versus a Rams’ defense that could get Aaron Donald back. If AD returns, Donald, Jonah Williams, Jalen Ramsey, and Leonard Floyd will be on the field at the same time.

In addition, Baker Mayfield could provide the same fireworks against Green Bay that he did versus the Raiders because the Packers’ defense is nothing to write home about. The Rams are a solid pick and the SU odds make them an overlay.

NFL Week 15 Pick: Los Angeles Rams +265