Arizona vs USC Odds and Betting Prediction for the Week 6 Game

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In the Pac-12, the Arizona Wildcats head on the road to take on the USC Trojans on Saturday. The Arizona Wildcats are 3-2 on the season, coming off a tough loss at home to the Washington Huskies.

For USC, they come into the game ranked 9th in the most recent Associated Press poll.

The Trojans are 5-0 on the season, coming off a win on the road at Colorado. The last time these two teams played, the Trojans beat the Wildcats 45-37 just under a year ago.

The USC Trojans are big favorites in this game. USC is listed at -22, with 72.5 points for the affair on Saturday night.

Check out the lines on College Football that MyBookie has for this game, plus the betting analysis and free pick for USC Trojans versus Arizona Wildcats.

Arizona vs. 9 USC Odds and Betting Prediction for the Game | MyBookie Week 6 Regular Season Preview

Arizona Wildcats vs. USC Trojans | NCAAF Week 6
ATS Odds: USC -22
Money line Odds: USC -2500 / Arizona +1025
Over/Under Odds: 72

Saturday, October 7th at 10:30 pm ET | ESPN
Los Angeles Memorial Coliseum, Los Angeles, CA

Deadly Offensive Combination

Lincoln Riley and Caleb Williams are a dangerous combination. In what could be the most lethal offense in all of College Football have not seen a game this season where they have scored less than 42 points. The Trojans are averaging 53.6 points per game on the season.

The passing game for the Trojans is putting up 382.4 yards per game. Caleb Williams threw his first interception in the win over Colorado. He has 21 touchdown passes.

Tahj Washington leads the statistics for the Trojans receivers, but there are so many it’s hard to keep track of which one has the best game. MarShawn Lloyd is the top running back for USC. He has 52 carries, 433 yards and three touchdowns.

The Trojans are on the road at Notre Dame next week before returning home to host Utah on October 21st.

Arizona Seeking Monster Upset

Undoubtedly, the Arizona Wildcats winning this game on the road would be the biggest upset the College Football season has seen so far. The Wildcats’ first season loss was on the road at Mississippi State.

Then, the loss to Washington came when Michael Penix Jr. ripped the Wildcats’ defense apart. Penix and Williams from USC are the top two candidates for the Heisman.

Arizona is led by Jayden de Laura. The signal-caller has thrown nine touchdown passes on the season. Tetairoa McMillan has caught five of them. The Wildcats passing attack is throwing for 273.6 yards per game. Arizona is scoring 26.4 points per game and allowing 19.

The Arizona schedule shows them on the road in back-to-back games. Next week, they head to Washington State to take on the unbeaten Cougars.

USC Wins Big on Saturday Night

Lincoln Riley knows keeping teams in games is not a recipe for long-term success. Do not expect the USC Trojans to let the Arizona Wildcats hang around in this game.

Caleb Williams wants to continue increasing numbers that no one can touch in College Football. He wants the Heisman Trophy to belong to him. He will have a monster game at home against the Arizona defense. The Trojans can throw up some numbers over the next few weeks.

The final bet for this game is the home team wins big. Take USC -22 over Arizona, with a final score prediction of 51-24 Trojans over Wildcats.

NCAAF Week 4 Pick: USC Trojans -22 | Bet Arizona vs. USC Today
MyBookie Betting Lines for the Game

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Enjoy this game and all the games for Week 6 of the College Football season. It could be the best slate of games all season!

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