10 College Football Matches With The Highest Betting On the Line

10 College Football Matches With The Highest Betting On the Line

The 2021 college football season is just a few months away, and the excitement is already building. The COVID-19 pandemic ruined some terrific non-conference matchups and also shortened conference schedules.

Things are back to normal in 2021, and the schedule is loaded with some big games. Here are 10 NCAA Football games with big stakes this season. 

Ten NCAA Football Games With The Highest Stakes This 2021 Season

Week 1: Georgia Bulldogs vs. Clemson Tigers

Two of the best college football programs in the country will meet up to start the season in a game that will be played in Charlotte. The winner of this game will earn a huge resume-boosting win, but the loser will still have time to rebound and reach the College Football Playoff.

Week 2: Oregon Ducks at Ohio State Buckeyes

The Pac-12 Conference needs a signature win early in the season, and the Oregon Ducks will have a chance against Ohio State. The Buckeyes reached the title game a season ago, but this roster will also look extremely different this season.

Week 3: Alabama Crimson Tide at Florida Gators

This is a rematch of last year’s SEC Championship Game and a chance for Florida to get some revenge at home. The SEC is going to be loaded with great teams again, and one loss is going to be extremely difficult to overcome. 

Week 4: Notre Dame Fighting Irish vs. Wisconsin Badgers

This might be the toughest game of the season for each team, and a loss in this game will likely keep the losing team from reaching the CFP. Soldier Field will host this classic matchup, and it should be a great early-season matchup. 

Week 6: Oklahoma Sooners vs. Texas Longhorns

The annual Red River Rivalry Game wasn’t decided until the 4th overtime a season ago, and this should be another great matchup. The winner of this game will have an inside track at winning the Big 12 Conference title this season.

Week 7: Miami Hurricanes at North Carolina Tar Heels

If someone other than Clemson is going to win the ACC this season, it will likely be either the Miami Hurricanes or North Carolina. This game will have plenty of hype to it, and Miami will also be looking for revenge after being embarrassed by North Carolina a season ago. 

Week 8: Ohio State Buckeyes at Indiana Hoosiers

Indiana nearly stunned Ohio State a season ago, but this time they will get to play the game on their home turn. The Indiana Hoosiers have a chance to be a top-10 team this season, but they will have to upset the Buckeyes if they want to win a Big Ten title. 

Week 10: LSU Tigers at Alabama Crimson Tide

This game is always one of the biggest of the season, even if there isn’t an SEC championship at stake. Alabama crushed LSU a season ago, but the LSU Tigers should be much more competitive this time around. This is also a series that has seen plenty of upsets over the years. 

Week 12: Iowa State Cyclones at Oklahoma Sooners

Iowa State and Oklahoma are expected to be the two best teams in the Big 12 Conference this season, and this game could have massive playoff implications. This could be one of the biggest games of the year if a Big 12 title is on the line. 

Week 13: Ohio State Buckeyes at Michigan Wolverines

Ohio State has beaten Michigan eight straight times, and they have done so in convincing fashion. The Michigan Wolverines will get to host this rivalry game this season, and they could do so with a chance to spoil a perfect season for Ohio State. 


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