Betting NFL Game Lines for 49ers vs Packers NFC Pick

The 49ers head to Lambeau Field this Sunday to take on the Packers in a pivotal NFC matchup, with NFL game lines locked in and both teams battling for key playoff positioning.

Betting 2024 NFL Week 12 Pick for the 49ers vs Packers
NFL Week 12 Firestorm: 49ers vs. Packers – Who Will Reign Supreme?

2024 NFL Season | 104th season of National League in the United States

Betting 2024 San Francisco 49ers at Green Bay Packers | Week 12 NFC showdown

The 49ers will play the Packers this Sunday as both teams want to help their playoff chances.

The Packers have not done well against the 49ers in recent games but hope to turn that around.

Both are dealing with injuries as the stakes are high for this NFC showdown.

NFL Week 12: San Francisco 49ers (5-5) at Green Bay Packers (7-3)
Sunday, November 24th, 2024 at 4:25 PM EST FOX | Lambeau Field, Green Bay

Betting Odds
The betting odds highlight how close the matchup is expected to be:

ATS Odds: Green Bay -2
Money line Odds:v49ers +107, Packers -131
Over/Under Odds: 47.5

Writer’s Breakdown and Pick for the 49ers vs Packers Game

Betting on the Green Bay Packers

Green Bay’s defense has struggled to create pressure, which could be a concern against San Francisco.

Brenton Cox Jr. made some key plays in the last game and could be a factor again.

Special teams might play a role in the outcome.

The Packers have been steady on field goals and their offense needs to finish drives when getting close to scoring.

Their home success against the 49ers could help their mindset.

If they run the ball well early, it might give Jordan Love more chances to make plays.

Betting on the San Francisco 49ers

The 49ers are looking to bounce back after the Seahawks game.

Brock Purdy is expected to play despite dealing with shoulder soreness. (Check out more Quarterback Matchups for NFL Week 12))

San Francisco’s defense has been strong, but they’ve allowed too many late-game points this season.

Ball control will be essential for the 49ers.

They will look to control the clock by leaning on their running game and short passing plays.

Limiting mistakes and penalties will also be critical as they try to take down the Packers on the road.

The 49ers’ coaching staff has emphasized tightening up defensive schemes to limit big plays.

With playoff hopes on the line, Niners must execute cleanly in all phases of the game to stay competitive.

Key Players to Watch

Christian Watson (Packers):
He will likely be a main option for Jordan Love.
Brock Purdy (49ers):
Quick decisions will help him handle Green Bay’s defense.
Christian McCaffrey (49ers):
He’ll be important in keeping the offense balanced, it may be tough for Green Bay to slow him down.
Brenton Cox Jr. (Packers):
A solid game here would boost his role on the team.

San Francisco 49ers vs. Green Bay Packers Prediction

It will all come down to which team can control the scrimmage.

While the Packers are favorites, but San Francisco’s experience in big games gives them a chance to pull off the upset.

This should be a close game, with both teams fighting until the final whistle.

Final Score Prediction: 49ers 27, Packers 24

Look for more top NFL Rivalries in NFL: Will They Play this Season

49ers vs. Packers Betting Pick

The Packers and 49ers have a history of close games, and this one looks like more of the same.

Green Bay will try to use home-field to their advantage, while San Francisco’s all-around approach keeps them in the fight.

Enjoy the action — and good luck with your bets.

NFL ATS Pick: San Francisco +2
NFL Total Pick: Under 47.5

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49ers vs Packers Trends and Insights

Brock Purdy has hit the Rushing Yards Over in 13 of his last 18 games I
Jauan Jennings has hit the Receptions Over in 10 of his last 14 games
Tucker Kraft has hit the Receptions Over in 12 of his last 18 games
Jordan Love has hit the Pass Attempts Under in 11 of his last 16 games
49ers have hit the 3Q Game Total Over in 14 of their last 19 games
49ers have covered the 1Q Spread in 8 of their last 10 away games
49ers are 5-5 when betting on the Moneyline
49ers are 5-5 when betting the Over
Packers have covered the 1Q Spread in 16 of their last 21 games
Packers have hit the Moneyline in 14 of their last 21 games
Packers are 4-5 when betting the Over for -1.5 Units / -13.64% ROI
Packers are 5-4 when betting the Under

Packers vs. 49ers Series History

Last meeting:
49ers 24, Packers 21: January 20th, 2024: NFC Divisional Playoff Game – Levi’s Stadium, Santa Clara, CA

Head-to-head (includes postseason games):
Green Bay Packers lead series 38-34-1

We have SNOW at Lambeau Field, which might continue to the #Packers vs. #49ers game this Sunday in Green Bay.

Snow games are BACK!

(🎥 @WesHod)pic.twitter.com/anpaQpsZvd
— Dov Kleiman (@NFL_DovKleiman) November 21, 2024