NFL Week 13 Picks & Predictions | MyBookie Expert SU, ATS & O/U Bets

Since 2008, D.S. Williamson has written about sports and sports handicapping.

His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to sportsbook odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.

Beating the Detroit Lions on Thanksgiving is almost impossible.

Even when the Lions were bad in the 1980s and 1990s, they still managed to deliver on the holiday.

This Thanksgiving, the Detroit Lions are clearly the better team.

The Green Bay Packers still haven’t found a consistent rushing attack, which means Aidan Hutchinson and the Detroit pass rush can tee off on Jordan Love.

With the home-field edge and a more complete roster, Detroit should cover the spread with little trouble.

Writer’s Week 13 Pick: Lions -3 (Thanksgiving Edge)

Packers vs Lions Betting Lines

Kansas City Chiefs -3.5 at Dallas Cowboys

Dallas comes off a stunning come-from-behind victory over the Philadelphia Eagles in NFL Week 12. Dak Prescott, as he so often does, played a fantastic game and willed his team to a dramatic win.

This week, though, the Kansas City Chiefs are a different kind of challenge.

Kansas City is desperate at 6–5, and Andy Reid and Patrick Mahomes know they can’t afford a letdown in any remaining game.

Facing a Dallas Cowboys team on short rest and coming off an emotional win, the situational spot favors KC.

Expect the Chiefs to exploit a potential flat performance from Dallas and control this one late.

Writer’s Week 13 Pick: Chiefs -3.5 (Desperation Spot)

Chiefs vs Cowboys Betting Lines

Chicago Bears at Philadelphia Eagles -7

This number looks inflated given where both teams are right now. It’s tough to justify a Philadelphia Eagles team still searching for a true offensive identity being favored by a full touchdown.

The Chicago Bears have won 7 of their last 8, with the lone loss in that stretch coming on the road against the Baltimore Ravens. Chicago’s defense has gelled, and Caleb Williams has clearly found his rhythm.

Yes, the Eagles will score — but Chicago’s balance on both sides of the ball should keep this within the number and possibly set up a late upset.

Writer’s Week 13 Pick: Bears +7 (Live Dog)

Bears vs Eagles Betting Lines

Houston Texans at Indianapolis Colts -3.5

This is a classic spot to roll the dice on the underdog moneyline. The Colts’ offense will move the ball, but the Houston defense has shown a knack for tightening up in the red zone and forcing field goals instead of touchdowns.

The Texans get a major boost with C.J. Stroud expected back in the starting lineup, which should elevate an already improving attack.

The Indianapolis Colts had the game against Kansas City in the bag last week.

Sometimes teams simply don’t bounce back cleanly from gut-punch losses like that.

Even if Indy responds, the Colts’ defense could struggle to contain a suddenly surging Texans rushing attack.

The hook on the spread makes Houston highly playable — and a sprinkle on the moneyline isn’t out of line.

Writer’s Week 13 Pick: Texans +3.5 (Upset Alert)

Texans vs Colts Betting Lines

D.S. Williamson’s Week 13 NFL picks lean on desperation spots, inflated lines, and live underdogs. Track all the latest NFL betting odds at MyBookie and grab the best numbers before kickoff.

Henry is originally from Scotland but now resides in Metro Atlanta with his chef wife Penny.

As well as working as a Sports freelance writer, he also writes horror fiction.

Watson is the author of Karaoke Night, Crueller, and Off The Grid.

NFL Week 13 SU Picks

Let’s open Week 13 in the AFC North, where momentum is firmly on one side. The Baltimore Ravens are rolling and should continue their strong play against a Cincinnati Bengals squad struggling to keep pace.

The Carolina Panthers, rarely a strong wager this season, must travel cross-country to take on the Los Angeles Rams.

The travel and matchup both point strongly toward a Rams victory.

It also appears the Washington Commanders might need to turn to their backup quarterback this weekend — a shift that heavily benefits the Denver Broncos, who are well-positioned to capitalize.

NFL Week 13 SU Picks

Ravens vs Bengals – SU Pick: Ravens
Panthers vs Rams – SU Pick: Rams
Commanders vs Broncos – SU Pick: Broncos
Bet NFL Week 13 Odds

NFL Week 13 ATS Picks

Week 13’s ATS slate features tight margins and undervalued spots.

The showdown between the Houston Texans and Indianapolis Colts shapes up like a razor-close game. With that expectation, grabbing Houston at +3½ is the sharper angle.

The Atlanta Falcons head north to face the New York Jets. Expect limited offense, but Atlanta should still handle the 2½-point number.

On Black Friday, the Philadelphia Eagles should win the game — but the spread is another story. With the Chicago Bears playing much better football, Chicago +7 is the right move.

NFL Week 13 ATS Picks

Texans vs Colts – ATS Pick: Texans +3.5
Falcons vs Jets – ATS Pick: Falcons -2.5
Eagles vs Bears – ATS Pick: Bears +7
Bet NFL Week 13 Lines

NFL Week 13 O/U Picks

Totals this week include two potential shootouts and one grinder.

The matchup between the Kansas City Chiefs and Dallas Cowboys screams fireworks, making the OVER 51½ the top totals play of the week.

As mentioned in the SU picks, the Texans–Colts game should be tight, with long drives and fewer explosive plays — making UNDER 45½ the logical call.

The battle between the Buffalo Bills and Pittsburgh Steelers profiles as a game where points could come quickly on both sides. The OVER 48½ is the right side.

NFL Week 13 O/U Picks

Chiefs vs Cowboys – Pick: OVER 51.5
Texans vs Colts – Pick: UNDER 45.5
Bills vs Steelers – Pick: OVER 48.5
Bet NFL Week 13 Totals

Henry Watkins’ Week 13 selections bring together sharp SU calls, targeted ATS value, and totals rooted in matchup tempo. Stay locked in with the latest NFL betting odds all week long.