Winning Pick for Lions vs Colts: Breakdown of NFL Game Lines

The Detroit Lions, led by their explosive offense, head to Indianapolis in Week 12 to take on the Colts, and NFL game lines show that Detroit is favored to continue their dominance in the NFC North.

Betting 2024 NFL Week 12 Pick for the Lions vs Colts
NFL Week 12 Fever: Don’t Miss Out on the Betting Action

2024 NFL Season | 104th season of National League in the United States
Week 12: Thursday, November 21st – Monday, November 25th, 2024

Betting 2024 Detroit Lions at Indianapolis Colts | Week 12 Games

The Lions head to Indianapolis against the Colts.

Indianapolis is in the mix in the AFC South.

They are looking to build momentum after a narrow win against the Jets last week.

They’ll try to slow down a high-powered Detroit offense that has been unstoppable lately.

Betting on the Betting Odds

Detroit enters the game as a favorite.

Meanwhile, Indianapolis has covered in eight of their 11 games but faces a tough challenge against one of the league’s most complete teams.

Betting on the Detroit Lions

The Lions come into this game on an eight-game winning streak, the longest since 1934.

Detroit’s offense leads the league, scoring 33.6 points per game.

Jared Goff has been at the center of this success, rebounding from a rough outing two weeks ago with 412 passing yards and four touchdowns last week. (Check out more Quarterback Matchups for NFL Week 12.)

Betting on the Indianapolis Colts

Richardson avoided interceptions but struggled with ball security, fumbling twice.

Indianapolis’ offense has relied on Jonathan Taylor to establish the run.

Taylor has been solid but will need a big performance against Detroit’s defense.

Detroit Lions vs. Indianapolis Colts Pick & Prediction

This game looks favorable for the Lions.

If Detroit’s defense can limit big plays, they are well-positioned for another win.

Prediction: Lions 34, Colts 21

Look for more top NFL Rivalries in NFL: Will They Play this Season

Lions vs. Colts Betting Pick

The Colts and Lions always play competitive games, and Sunday’s matchup should be no different.

NFL ATS Pick: Detroit -7.5
NFL Total Pick: Over 50

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Lions vs Colts Trends and Insights

Jahmyr Gibbs has hit the Rushing Yards Over in 13 of his last 19 games
Jared Goff has hit the Passing Yards Over in 13 of his last 19 games
Joe Flacco has hit the TD Passes Over in 8 of his last 10 games
Kylen Granson has hit the Receptions Under in his last 7 games at home
Lions have hit the 3Q Game Total Over in 16 of their last 19 games
The Detroit Lions have covered the 1H Spread in 16 of their last 21 games
Colts have covered the Spread in 13 of their last 21 games
Colts have hit the 3Q Moneyline in 6 of their last 9 games at home
Lions are 9-1 when betting on the Moneyline
Lions are 5-4 when betting the Over
Colts are 5-6 when betting on the Moneyline
Colts are 5-6 when betting the Over

Colts vs. Lions Series History

Last meeting:
Lions 21, Colts 41: November 1st, 2020: Week 8 – Ford Field, Detroit, MI

Head-to-head (includes postseason games):
Indianapolis Colts lead series 22-20-2

DETROIT LIONS INJURY UPDATE

Sam LaPorta, Brodric Martin, Iffy Melifonwu, and Emmanuel Moseley are all OUT on Sunday vs. the Jaguars #OnePride pic.twitter.com/OfsXXC7z0E
— Crunch Time Sports (@officialctpod) November 15, 2024