2022 College Football Betting Analysis and Picks for the Best Games On Week 4

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Although college football kicks off on Thursday, Sep. 22, our top five picks for NCAAF Week 4 don’t play until Saturday, Sep. 24. This week, we’re concentrating on teams that have major advantages over their opponents. See below for College Football Odds, analysis, and picks for five games that should be on your betting radar.  

Top Five NCAA Football Games to Must Bet On Week 4 of the 2022-23 Season

2022 NCAA Football Week 4

• Thursday, Sep. 22 – Saturday, Sep. 24

Maryland Terrapins at Michigan Wolverines -17 | Saturday, Sep. 22

Undefeated Maryland is playing great football. But the Terps take a major step up in class on Saturday.

The Michigan Wolverines have scored 50 or more points in 3 straight. Sure, Maryland is by far the best team the Maize & Blue have played this season, but the game happens in the Big House and Michigan beat the Turtles 59-18 in the last head-to-head. Michigan rolls to a win and cover. 

NCAAF Week 4 Pick: Michigan Wolverines -17 

UCLA Bruins -21.5 at Colorado Buffalos | Saturday, Sep. 22

Colorado has lost 3 straight ATS and against the spread. TCU beat the Buffalos 38-13, Air Force dominated Colorado 41-10, and in their last, Minnesota blasted the Buffs 49-7.

UCLA struggled to a win over South Alabama in their last. South Alabama is a much better team than Colorado, though. So we should expect Chip Kelly’s squad to win this by 28 to 35.

NCAAF Week 4 Pick: UCLA Bruins -21.5 

Florida Gators at Tennessee Volunteers -10.5 | Saturday, Sep. 22

The line has already moved 3 points. The Vols opened -7.5. As of the Wednesday before kickoff, the line has moved to Tennessee -10.5.

Florida plays hard. But the Gators won’t hang with a Vols squad that might be third best in the SEC after Georgia and Alabama. The Vols are 3-0 SU and ATS while the Gators have failed to cover in their last 2. 

NCAAF Week 4 Pick: Tennessee Volunteers -10.5 

Arkansas Razorbacks +2.5 at Texas A&M Aggies | Saturday, Sep. 22

Arkansas, no doubt, has a huge edge at quarterback in this game. K.J. Jefferson leads an offense that averages over 500 yards and close to 38 points per game. 

The Razorbacks defense is a decent unit. More importantly, the Hogs D faces an offense that is searching for a real starter under center. Max Johnson played okay, but not great versus Miami in A&M’s last game. 

The Aggies have a fantastic defense, but it’s tough to win games consistently when you have trouble scoring. Texas A&M should be in some trouble in this game. Arkansas wins and covers.   

NCAAF Week 4 Pick: Arkansas Razorbacks +2.5 

Kansas State Wildcats at Oklahoma Sooners -12.5 | Saturday, Sep. 22

Kansas State looked great in wins over South Dakota and Missouri, but what happened in the Wildcats’ last? Tulane, not exactly a top football program, upset K-State on their field 17-10.

In week 4, the Wildcats must contend with an Oklahoma team that gets better by the week. The Sooners have improved big time on defense. Oklahoma allows less than 313 total yards and 10 points per.

The Sooners offense is catching up to the D. Oklahoma should blow by this spread. 

NCAAF Week 4 Pick: Oklahoma Sooners -12.5

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