College Football Week 7 Picks & Expert Best Bets

Week 7 of the college football season is here — and it’s packed with value for bettors chasing edges in every conference matchup.

The playoff race is heating up, and sharp bettors are locking in early on the best bookie odds before the lines move.

At MyBookie Sportsbook, our experts D.S. Williamson and Henry Watkins break down this week’s NCAAF picks and predictions, highlighting the smartest ATS, SU, and O/U plays.

MyBookie Writers’ College Football Week 7 Picks You Can’t Miss

Whether you’re betting with the spread or eyeing in-game swings, Week 7 offers plenty of opportunities to capitalize.

From SEC powerhouses to Big Ten grinders, every matchup matters — and the MyBookie sportsbook gives you the lines, stats, and live markets you need to stay ahead.

If you’re serious about winning in Week 7, you’ll want to dive into every one of these College Football bets.

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College Football Week 7 Expert Picks from D.S. Williamson & Henry Watkins

Our in-house analysts are back with another sharp slate. D.S. Williamson is rolling with Alabama, Oregon, Oklahoma, and Florida to cover, while Henry Watkins backs Alabama, Texas, and UNLV straight up—plus ATS calls on Oklahoma State, SMU, and Maryland, with totals across Ohio State vs. Illinois, Georgia Tech vs. App State, and Tennessee vs. Arkansas.

No hype, no distractions—just focused, data-driven Week 7 picks designed for bettors chasing value in the latest college football live betting odds at MyBookie Sportsbook.

D.S. Williamson | MyBookie Sports Writer

Alabama -4.5 at Missouri

Alabama exacted revenge over the Vanderbilt Commodores in a way that implies Kalen DeBoer’s program is on the rise.

Diego Pava and Vandy held their own for most of the game until the fourth quarter when Bama pulled away for a 30-14 victory.

Mizzou on the road is a tough assignment but the Tide is rolling at this point.

Alabama might be the best team in the country.

Another Bama win and cover is in the cards.

Indiana at Oregon -9.5

Dante Moore is the favorite to win the Heisman Trophy.

No doubt, the Oregon QB is happy he escaped the hellscape that is UCLA.

Not only that, but Oregon is incredibly difficult to beat, or seven stick with in Autzen.

As well as Indiana has played, the Hoosiers, which are a legit Top 25 team that plays in the Big Ten, have yet to face a team with the quality of the Ducks.

Dan Lanning’s squad should have no trouble handing Indiana at least a 10-point loss.

Oklahoma at Texas -3.5

Texas is the chalk because John Mateer, Oklahoma’s starting quarterback, is out with a hand injury.

Back up A.J. Hawkins doesn’t have the skills that Mateer has.

But, and this is big, Arch Manning is struggling behind a bad offensive line.

Texas isn’t a great football team.

It’s a team with a good defense but it’s not a great overall team.

The 3.5 points will mean something in this game.

So go with Oklahoma and Brett Venables D to force Arch into a few bad throws.

Sooners cover.

Florida at Texas A&M -8.5

Freshman Dallas Wilson stepped onto the field for the first time in a Gators uniform and look what happened?

The Gators upset Texas 29-21 in The Swamp.

This Saturday, Florida travels to College Station to take on the Aggies.

For sure, beating the Aggies will be tough but Wilson can’t be stopped.

Also, Florida’s D is much better than people realize.

The Gators keep this game much closer than the spread.

D.S. Williamson Week 7 Picks

Alabama -4.5 @ Missouri – Bet: Alabama covers
Indiana @ Oregon -9.5 – Bet: Oregon covers
Oklahoma @ Texas -3.5 – Bet: Oklahoma +3.5
Florida @ Texas A&M -8.5 – Bet: Florida +8.5
College Football ATS Lines

Henry Watkins | MyBookie Sports Writer

NCAAF Week 7 SU Picks

Alabama had a tough test last weekend, finally getting past Vandy in a close one.

I think they do more of the same this weekend against Missouri.

It has been a nightmare season for Texas, as they dropped out of the top 25.

They need a win in the worst way possible, and I think they get it against Oklahoma.

I have had some luck playing UNLV this NCAAF season, so I am going to go with them again this weekend in their matchup against Air Force.

Henry Watkins Week 7 SU Picks

Alabama @ Missouri – SU Pick: Alabama
Oklahoma @ Texas – SU Pick: Texas
UNLV @ Air Force – SU Pick: UNLV
College Football Moneyline Odds

NCAAF Week 7 ATS Picks

Let’s start with the matchup between Houston and Oklahoma State, where the Cougars are a clear favorite.

I loke Oklahoma State to cover as a 14 ½ point dog.

It has not been a great start to the season for Stanford, and I think we see them endure more pain this weekend.

I like SMU as a 19 ½ point favorite.

The matchup between Maryland and Nebraska strikes me as a potentially defensive struggle that stays close throughout.

I am taking Maryland +6 ½.

Henry Watkins Week 7 ATS Picks

Houston @ Oklahoma State – ATS Pick: Oklahoma State +14.5
Stanford @ SMU – ATS Pick: SMU -19.5
Maryland @ Nebraska – ATS Pick: Maryland +6.5
College Football ATS Lines

NCAAF Week 7 O/U Picks

I am a little on the fence with the Ohio State/Illinois matchup, as I think it will come close to the 50 ½ point total, but I ultimately feel it will fall UNDER.

Georgia Tech has been fun to watch this season, and I think we see another good one against App.

State this weekend, with the total going OVER 55 ½.

I certainly think we will see offensive fireworks in the game between Tennessee and Arkansas, but the 68 ½ point total seems high to me, hence the UNDER.

Henry Watkins Week 7 O/U Picks

Ohio State @ Illinois – O/U Pick: UNDER 50.5
Georgia Tech @ Appalachian State – O/U Pick: OVER 55.5
Tennessee @ Arkansas – O/U Pick: UNDER 68.5
College Football Over/Under Lines

Final Throughts on Betting College Football Week 7 & Betting Takeaways

Week 7 is shaping up to be one of the most unpredictable slates of the season — and that’s exactly where profits hide.

Stay sharp, follow the expert analysis, and get instant access to live betting odds through your MyBookie sportsbook login.

Bet smarter. Win bigger.

Stay sharp, follow the expert analysis, and get instant access to live betting odds through your MyBookie sportsbook login. Trust the bookie odds that keep you one play ahead — only at MyBookie.ag. College Football Week 7 odds to lock in the best lines and get set for a packed Saturday of action.