The domestic leagues across Europe are back in action, and while it is great to check in on those and make some wagers every weekend, it is the Champions League that draws more bets than most.
It is the largest, most lucrative tournament in the world, so it is no surprise that so many bettors want in on the action.
The format changed last year, with 32 teams playing in one large league, with each team playing 6 games.
The top 8 automatically move on, while teams 9 through 24 go into a playoff to fill the other 8 spots.
Matchday 1 will be played on Tuesday and Wednesday, and we are picking out a handful of games that we really like, so let’s get to our predictions for those games.
Athletic Club Vs Arsenal
This is an earlier start that most, with this game kicking off at 12:45 PM EST on Tuesday.
Athletic Club are off to a rough start to the season and come into this one on the heels of back-to-back loses.
Arsenal has won 3 of their opening 4 games in the Premier League, with their lone loss coming at the hands of Liverpool, who are the only team with a 100% record to start the season.
The home side is struggling to find the net, but they are also defensively solid, so it is going to be tough for the Gunners to break them down, but I do like Arsenal to edge it.
Athletic Club 0 Vs 1 Arsenal | Bet this Bet UEFA Champions League Match
Real Madrid Vs Marseille
You have to say that last season was a disappointing one for Madrid, as they crashed out of the tournament relatively early.
They are off to a winning start to the LaLiga season, coming into this game with a 100% record, although most of their wins have not been particular convincing.
Marseille is a little tougher to figure out, going 2-2 to start the season.
That said, their losses have come on the road, while their convincing wins have come at home.
You have to give the edge to the home team here.
Real Madrid 3 Vs 1 Marseille | Bet this Bet UEFA Champions League Match
Bayern Munich Vs Chelsea
We move to Wednesday for the next pair of games, both of which are absolutely fantastic.
Bayern returned to the top of the Bundesliga last season, winning it comfortably, and they seem to be very tough to beat again this season.
They have a perfect record this season and are scoring for fun, but this is certainly stiffer competition than what they have faced to this point.
Chelsea is not really living up to the preseason hype at the moment, although they are unbeaten through their first 4 games.
They are coming off a 2-2 tie with Bournemouth this past weekend.
I think we get a lot of goals in this one.
Bayern Munich 3 Vs 2 Chelsea | Bet this Bet UEFA Champions League Match
Champions League Odds provided by MyBookie
Liverpool vs Atletico Madrid
As mentioned earlier, the current Premier League champions are off to a perfect start to the new season.
They are coming off a 1-0 win over Burnley this past weekend, but they needed a late penalty win against the EPL new boys.
Still, they are always tough to beat at home, especially on European nights.
Atletico started the season with a surprising loss, but they have bounced back with a win and 2 ties.
As always, they will look to set out a defensive stall in hopes of frustrating the opposition, but that Liverpool firepower is going to be tough to stop.
Liverpool 2 Vs 0 Atletico Madrid | Bet this Bet UEFA Champions League Match
Tuesday ✅
— UEFA Champions League (@ChampionsLeague) September 15, 2025
Wednesday ✅
Thursday ✅
The Champions League is back #UCL pic.twitter.com/GR1GIJ45en
Elevate your NFL Season with MyBookie + Loyalty Rewards Program
Start to earn points with the Sportsbook and Casino Loyalty Program to level up, get exclusive bonuses and rakeback in every stage of the 2025/26 Season: Draft, Offseason, Preseason, Regular Season, Playoffs and Super Bowl.
Join the MyBookie program, subscribing will guarantee your share of $15,000 in free plays.
Bet On NFL top betting odds, anywhere, anytime
Learn more on Betting on Football: Everything You Need to Know About Handicap Soccer Betting
Soccer Betting Center
Soccer Odds and Lines
World Cup Odds |
UCL Odds | UEL Odds |
EPL Odds | Serie A Odds |
Bundesliga Odds |
La Liga Odds | Ligue 1 Odds |
Premier League |
Champions League |
World Cup |
EUROCup |
Copa America |
- UEFA Champions League Top Games to Bet On This Week: Group Betting
- The Unbeatable Parlay: A UEFA Longshot, a CONCACAF Underdog, and a CONMEBOL Surprise
- Your Essential Guide to Researching & Winning Liga MX Bets
- Understand Club World Cup: Strongest Contenders and Key Dates
- Liga MX Contenders, Key dates and Who will Win the Apertura 2025
- Do you Know the Premier League Table with favorites to Win?
- Choose your top FIFA Club World Cup games in Group Stage