NCAAF Week 10 Against the Spread Lines & Picks for this Week

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The first College Football Playoff Rankings landed with some surprises. Ohio State is the number one team followed by Georgia in second, Michigan in third, and Florida State in fourth.

The Buckeyes hope to continue impressing the Selection Committee when Ohio State travels to Rutgers on Saturday to take on the Scarlet Knights.

Check out College Football against the spread odds, analysis, and a pick for Ohio State at Rutgers along with the other top matchups happening in College Football Week 10.

2023 College Football Week 10 ATS Picks | MyBookie Regular Season Betting Preview

2023 NCAA Division I FBS football season | 154th season of college football in the United States
NCAAF Week 10: Tuesday, October 31st – Saturday, November 4th, 2023

1 Ohio State Buckeyes at Rutgers Scarlet Knights

ATS Odds: Ohio State -18.5
Saturday, November 4th, 2023 at 12:00 pm | CBS
SHI Stadium, Piscataway, NJ

Ever since an impressive road victory over Notre Dame, Ohio State has shown they have what it takes to win the National Championship. The Buckeyes beat Maryland 37-17, Purdue 41-7, Penn State 20-12, and Wisconsin 24-10. Bucks roll.

College Football Week 10 ATS Pick: Ohio State Buckeyes -18.5 | Bet Ohio State at Rutgers Today
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23 Kansas State Wildcats at 7 Texas Longhorns

ATS Odds: Texas -4
Saturday, November 4th, 2023 at 12:00 pm | FOX
DKR-Texas Memorial Stadium, Austin, TX

Texas is just a 4 point favorite because Kansas State has won 3 straight by scoring more than 40 points. The Wildcats dropped 41 onto TCU in a 41-3 win a couple of games ago and beat Houston 41-0 in their last. The Longhorns could lose this straight up.

College Football Week 10 ATS Pick: Kansas State +4 | Bet Kansas State at Texas Today
MyBookie Betting Lines for the Game

12 Missouri Tigers at 2 Georgia Bulldogs

ATS Odds: Georgia -15.5
Saturday, November 4th, 2023 at 3:30 pm | CBS
Sanford Stadium, Athens, GA

Georgia can cover this spread. However, the Bulldogs won’t. Why?

Missouri has one of the top offenses in the SEC. The defense is also decent. So although Georgia will win, they may only win by 14, which makes the Tigers the team to back to cover the spread.

College Football Week 10 ATS Pick: Missouri Tigers +15.5 | Bet Missouri at Georgia Today
MyBookie Betting Lines for the Game

9 Oklahoma Sooners at 22 Oklahoma State Cowboys

ATS Odds: Oklahoma -6
Saturday, November 4th, 2023 at 3:30 pm | ACCN Network
Boone Pickens Stadium, Stillwater, OK

It’s impossible to back the Oklahoma Sooners to win straight up much less cover a 6-point spread against one of their top rivals on the road.

Brett Venables’s team lost to Kansas in their last. Before losing to the Jayhawks, Oklahoma barely beat UCF, and before that, the Sooners almost lost to Texas.  

College Football Week 10 ATS Pick: Oklahoma State Cowboys +6 | Bet Oklahoma at Oklahoma State Today
MyBookie Betting Lines for the Game

Virginia Tech Hokies at 13 Louisville Cardinals

ATS Odds: Louisville -9.5
Saturday, November 4th, 2023 at 3:30 pm | ACCN Network
Cardinal Stadium, Louisville, KY

Louisville fumbled their chances of making the College Football Playoff in a stunning loss to Pittsburgh. But the Cardinals, who beat Notre Dame a few games ago, bounced back with a 23-0 win over ranked Duke.

Virginia Tech has played competitive football in their last couple, but they have no shot of keeping it close versus Louisville. The Cardinals roll.

College Football Week 10 ATS Pick: Louisville Cardinals -9.5 | Bet Virginia at Louisville Today
MyBookie Betting Lines for the Game

5 Washington Huskies at 20 USC Trojans

ATS Odds: Huskies -3.5
Saturday, November 4th, 2023 at 7:30 pm | ABC
Los Angeles Memorial Coliseum, Los Angeles, CA

For sure, Washington has struggled against bad teams, but the Huskies step it up versus top competition and Washington views USC as top competition.

The Trojan D has no shot of stopping Washington from scoring 50 to up to 63. USC won’t keep pace.

College Football Week 10 Pick: Washington Huskies -3.5

College Football Week 10 ATS Pick: Alabama Crimson Tide -3 | Bet Washington at USC Today
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14 LSU Tigers at 8 Alabama Crimson Tide

ATS Odds: Alabama -3
Saturday, November 4th, 2023 at 7:45 pm | CBS
Bryant-Denny Stadium, Tuscaloosa, AL

LSU’s D has played better in their last 2 games. But those matchups were versus Auburn and Army.

On Saturday, LSU takes on one of the better teams in the nation. Alabama has gotten better and better. We shouldn’t downplay how the Tide outscored Tennessee 27-0 in the second half of their last victory.

College Football Week 10 Pick: Alabama Crimson Tide -3

College Football Week 10 ATS Pick: Alabama Crimson Tide -3 | Bet LSU at Alabama Today
MyBookie Betting Lines for the Game

19 UCLA Bruins at Arizona Wildcats

ATS Odds: Bruins -2.5
Saturday, November 4th, 2023 at 10:30 pm | FS1
Arizona Stadium, Tucson, AZ

UCLA shouldn’t be favored in this. Arizona is the better team and this happens in Tucson.

The Wildcats have lost 43-41 to USC in Los Angeles in a double overtime game, blasted Washington State 44-6, and taken down then 11 Oregon State 27-24 in their last. UCLA beat Stanford and Colorado in their last couple of games. Zona beats the Bruins by 6 or more.

College Football Week 10 ATS Pick: Arizona Wildcats +2.5 | Bet UCLA at Arizona Today
MyBookie Betting Lines for the Game

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Good luck with all your College Football picks. We hope our look at the Week 10 Against the Spread picks in College Football helps you make your picks for the week. Enjoy!

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