NFL 2022 Buffalo Bills Win/Loss Odds Analysis and Betting Prediction

NFL 2022 Buffalo Bills Win/Loss Odds Analysis and Betting Prediction

The Buffalo Bills are hoping that the old saying “the third time’s a charm” is true. The last two seasons, the Bills Super Bowl hopes were dashed by the Kansas City Chiefs. However, this year could be different. The Bills have been made the preseason favorites to win the Lombardi Trophy, and they have the personnel that is capable of doing that. The Bills haven’t been back to a Super Bowl since they lost four straight from 1990-1993. This could finally be the year that they return to the big game. Let’s take a look at the 2022 Buffalo Bills so you can get all set and plan your bets against the NFL Team Totals odds.

Can the Bills Finally Get Back to the Super Bowl? | NFL Betting

A 12 Win Season?

The oddsmakers are high on the Bills this season, and they’ve made their predicted win total number at 11.5. This is the highest win total prediction in the league this season. Buffalo is capable of eclipsing that number, but they’re going to have some tough games along the way.

Buffalo opens the season traveling across the country to take on the defending Super Bowl champions, the Los Angeles Rams. And unfortunately for the Bills, it doesn’t get any easier from there. They then host a Tennessee team that made the playoffs last season. In Week 3 they head to South Beach to play a vastly improved Dolphins squad. They then head to Baltimore, host the Pittsburgh Steelers, and then take a trip to play their old friends, the Kansas City Chiefs.

Following their bye week, they have a date with the Green Bay Packers in Buffalo. They then have an easier stretch of games with the New York Jets, Minnesota Vikings, Cleveland Browns, and Detroit Lions. They then travel to New England, play the Jets again, host the Dolphins, then play the Chicago Bears.

Buffalo will have a tough ending to their season. In Week 17, they’ll travel to Cincinnati to take on the defending AFC champion Bengals. They’ll end the season in Buffalo, as they host their hated rivals, the New England Patriots.

As long as the Bills can stay healthy, 12 wins are in their sight. They have a very tough schedule, but this is the best Bills team since the mid-90’s. We’ll see if they have what it takes to make another Super Bowl run.

A Great Offseason

Buffalo already had a very good team, but they decided that the 2022 season was going to be “Super Bowl or Bust”. The biggest signing that they made was getting free agent linebacker Von Miller. Miller won a Super Bowl with the Rams last season. Even though he’s not as good as he once was, he’s still capable of getting to the quarterback, and being a difference-maker on the defensive side of the ball.

The Bills also acquired defensive tackles DaQuan Jones and Tim Settle to solidify their front. The Bills already had a very good front line, but now they have more strength and depth up front to stop the run and get to the quarterback. 

Jamison Crowder and OJ Howard were signed to help Josh Allen and the passing attack. They also signed offensive linemen Rodger Saffold and Dan Quessenberry to give the line more depth. Allen is one of, if not the best quarterback in the league, and the Bills gave him more skill players and more offensive linemen to protect him.


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