MNF Rams vs 49ers Odds Analysis for Week 4 of the 2022 NFL Season

MNF Rams vs 49ers Odds Analysis for Week 4 of the 2022 NFL Season

Written by on October 3, 2022

One of the top rivalries in the NFL happens on Monday night when the Los Angeles Rams head up the Pacific Coast Highway to Santa Clara to take on the San Francisco 49ers. San Francisco has started the season 1-2. So the home team is motivated for a victory. Will Jimmy G. lead the Niners to a victory and cover? Or will Matthew Stafford and the defending champs pull off the upset win? See below for NFL Lines, analysis, and a free pick for Rams at 49ers. 

NFL Week 4 Betting Preview for Los Angeles Rams at San Francisco

Monday Night Football: LA Rams versus San Francisco Odds and Match Info

Why bet on LAR versus San Francisco?

After their first game, where Buffalo decimated the Rams 31-10 at Sofi Stadium, Los Angeles had every right to fold. Instead, the Rams rallied for 2 straight victories. The victory in NFL Week 3 impressed big time because it happened versus NFC West rival Arizona and it happened on the road. Los Angeles knows San Francisco is their top competition for the division. Expect the Rams to be fired up to win this. 

Los Angeles Rams Offensive Averages

  • Total Yards: 306.3
  • Passing Yards: 234.0
  • Rushing Yards: 72.3
  • Points Scored: 20.3
  • Turnovers: 7

Los Angeles Rams Defensive Averages

  • Total Yards: 346.3
  • Passing Yards: 252.7
  • Rushing Yards: 93.7
  • Points Scored: 23.3
  • Takeaways: 7

Why bet on San Francisco versus LAR?

In week 3, San Francisco blew a lead versus the Denver Broncos. The 49ers had no business losing the game. To be fair, the contest happened in Denver. Not only that, but Jimmy Garoppolo didn’t expect to start this season. Jimmy G. should run the offense much better on Monday night. The Niners have a real shot of beating the Rams. 

San Francisco 49ers Offensive Averages

  • Total Yards: 323.7
  • Passing Yards: 172.7
  • Rushing Yards: 151.0
  • Points Scored: 15.7
  • Turnovers: 5

San Francisco 49ers Defensive Averages

  • Total Yards: 227.0
  • Passing Yards: 148.3
  • Rushing Yards: 78.7
  • Points Scored: 12.3
  • Takeaways: 3

Rams at 49ers Relevant Trends

  • Rams are 4-1 ATS in their last 5 Monday night games
  • LAR is 1-4 ATS in their last 5 games
  • Under is 4-1 in the Rams’ last 5 games
  • 49ers are 5-0 ATS in their last 5 games at home
  • San Francisco is 6-1 ATS in their last 7 versus the NFC
  • Under is 7-0 in the 49ers’ last 7 on grass

Los Angeles Rams at San Francisco 49ers Final Betting Prediction

If you liked the Rams or 49ers before Monday, nothing happened over the weekend or this morning that will convince you other wise. But if you do like LAR, you must take into consideration a couple of factors.

First, the Rams’ rushing attack is close to nonexistent. Second, Los Angeles has turned the ball over 7 times this season while the 49ers field the most opportunistic defense in the league. 

There are other things to think about. Even with Jalen Ramsey on the field, the Rams rank twenty-first against the pass. Then there’s the trend that tells us the Niners cover at home.

One trend that we didn’t add to this blog but is also significant is how San Francisco has covered in the last 5 head to head meetings. All things considered, SF is the bet to win and cover. 

NFL Week 4 Pick: San Francisco 49ers -1.5 


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