2023 49ers vs Eagles Odds and Betting Analysis for this Week 13 Matchup

2023 49ers vs Eagles Odds and Betting Analysis for this Week 13 Matchup

We have a rematch of the NFC Championship, as the San Francisco 49ers and Philadelphia Eagles are set to get together on Sunday in the National Football League. We also have two of the top teams again in 2023 setting to square off. The 49ers are coming into the game on a three game winning streak. After winning their first five, then losing their next three, the 49ers have gotten hot once again. San Francisco is coming off a blowout win over Seattle on Thanksgiving Day.

MyBookie offers the NFL odds, game analysis, and betting pick for the San Francisco 49ers versus the Philadelphia Eagles.


49ers vs Eagles Odds and Betting Prediction for this Week 13 Matchup | MyBookie NFL Regular Season Preview

San Francisco 49ers vs Philadelphia Eagles | NFL Week 13
ATS Odds: 49ers -3
Money line Odds: San Francisco 49ers Line: -130 / Philadelphia Eagles Line: +155
Over/Under Odds: 47.5

Sunday, December 3rd, 2023 at 4:25 pm ET | FOX
Lincoln Financial Field, Philadelphia, PA


Heading into the Game | 49ers vs Eagles

For the Philadelphia Eagles, they have won five straight games. The lone loss for the Eagles this season was to the New York Jets. Philadelphia is coming off an overtime win at home over the Buffalo Bills. The Eagles are playing their fourth straight against one of the best teams in the league. They already beat Dallas, Kansas CIty and Buffalo, and now have the 49ers.

The San Francisco 49ers are favorites in this game, despite being on the road. The 49ers are -3 at Philadelphia. The total for this game is listed at 45.5 points. This is actually the second game this season that the Philadelphia Eagles come into the game as underdog. The other game as at Kansas City, in which they won the game straight up.

The win for the 49ers pushed them two games up on Seattle in the NFC West. The 49ers are tied with Detroit for the second seed in the NFC.


Hurts Leading MVP Race

Jalen Hurts is the frontrunner to win the 2023 Most Valuable Player in the NFL. The signal caller has been tremendous for the Eagles this season. Not only has Hurts tossed for nearly 2,700 yards and 18 touchdowns, but he is also second on the team with 410 rushing yards and 11 touchdowns.

The Eagles have loved their move to D’Andre Swift at running back. They were able to let Miles Sanders go, and Swift has been terrific. The running back has 161 carries for 770 yards and four touchdowns on the season. Kenneth Gainwell is next in line with 202 yards and two touchdowns on the season.

A.J. Brown is the top target for Hurts. The receiver has been at the top of the list of elite receivers in the league. Brown has 73 receptions for 7 touchdowns, with over 1,000 yards. If he is not having a great game, DeVonta Smith is 68 yards away from 800 on the season, and has five touchdowns as well.


Defense is Sharp

Haason Reddick and Josh Sweat lead the defensive charge for Philadelphia. Reddirck has 8.5 sacks and Sweat has 6.5. The Eagles have 32 as a team. Philadelphia has one touchdown on the defensive side, as veteran cornerback Darius Slay returned an interception for a touchdown earlier in the season. The Eagles have six interceptions and have caused 8 fumbles on the season.


Eagles Wrapping up Regular Season

The Philadelphia Eagles will go to the postseason. The only question is what seed and where will they start. The Eagles before that have back to back trips to Dallas and Seattle, before coming home to host the Giants and Cardinals. Philadelphia then ends the season at the New York Giants.


Purdy Still Balling

Brock Purdy, the former Iowa State Cyclones signal caller continues to impress. The 49ers have been confident in his abilities, and he has continued to prove them right. He has thrown for over 2,800 yards and 19 touchdowns, with just 6 interceptions on the season. Brandon Aiyuk is just 119 yards shy of 1,000 on the season.

Deebo Samuel and George Kittle are both elite pass catchers as well for the 49ers. Kittle has 667 yards and give touchdowns, while Samuel has 474 yards and a touchdown. The 49ers then have Christian McCaffrey, who has 48 receptions on the season, and also five touchdowns via the pass.

McCaffrey also has carried the football 193 times for 939 yards and 11 touchdowns. If he is not getting the ball, Elijah Mitchell and Samuel will get opportunities. The 49ers rank 7th in the National Football League with 136 rushing yards per game.


49ers Defensive Unit

You cannot talk about the San Francisco 49ers without talking about their defense. The 49ers are an elite bunch on that side of the ball as well. The 49ers are led by Nick Bosa, and his 8 sacks. Javon Hargrave has been great as well with 6, while Arik Armstead has 5. Fred Warner and Talanoa Hufanga both have three interceptions to lead the team. The 49ers defense has yet to score a touchdown this season, which comes as a surprise for such a solid unit.


San Francisco Remaining 2023

The 49ers will host the Seahawks next week, before a trip to Arizona against the Cardinals. The final three games for San Francisco before the postseason are at home against the Ravens, on the road at the Commanders and then Week 18 is at home against the Rams.


Eagles and 49ers Clash in Massive Showdown

This is going to be another great game in the National Football League. It’s hard to bet against each of these two teams. We could see both teams winning the Super Bowl this season. But, when push comes to shove, seeing the best team in the league as the home underdog just does not make sense to us. We are betting the Philadelphia Eagles +3. 

This gives us the chance to still win the bet if the 49ers win late by a point or two. Even by a field goal, and we push. It makes too much sense to NOT bet on the Eagles in this game. The final bet for this game is the Philadelphia Eagles +3 over the San Francisco 49ers. Good luck with all your betting and enjoy the big game!

2023 NFL TNF Pick: ATS Philadelphia Eagles +3 | Bet 49ers vs Eagles
MyBookie Betting Lines for the Game


San Francisco 49ers Team

8-3 | 4-2 Away

San Francisco 49ers Last 5

Date OPP Result
11/23/23 @ SEA W31-13
11/19/23 vs TB W27-14
11/12/23 @ JAX W34-3
10/29/23 vs CIN L31-17
10/23/23 @ MIN L22-17

San Francisco 49ers Injury Report

Name | Position Status Date
Ray-Ray McCloud III WR Questionable Nov 29
Jordan Mason RB Questionable Nov 29
Arik Armstead DE Questionable Nov 29
Spencer Burford OT Questionable Nov 28
George Odum S IR Nov 27

Philadelphia Eagles Team

10-1 | 5-0 Home

Philadelphia Eagles Last 5

Date OPP Result
11/26/23 vs BUF W34-34 OT
11/20/23 @ KC W21-17
11/5/23 vs DAL W28-23
10/29/23 @ WSH W38-31
10/22/23 vs MIA W31-17

Philadelphia Eagles Injury Report

Name | Position Status Date
Zach Cunningham LB Questionable Nov 29
Julio Jones WR Questionable Nov 29
D’Andre Swift RB Questionable Nov 29
Dallas Goedert TE Questionable Nov 29
DeVonta Smith WR Questionable Nov 29

2023 NFL Standings up to Week 13

NFC West Standings | San Francisco 49ers

Team W L PCT Strk
San Francisco 49ers 8 3 .727 W3
SEASeattle Seahawks 6 5 .545 L2
Los Angeles Rams 5 6 .455 W2
Arizona Cardinals 2 10 .167 L2

NFC East Standings | Philadelphia Eagles

Team W L PCT Strk
Philadelphia Eagles 10 1 .909 W5
Dallas Cowboys 8 3 .727 W3
New York Giants 4 8 .333 W2
Washington Commanders 4 8 .333 L3

San Francisco 49ers vs Philadelphia Eagles Betting Trends

  • San Francisco are 8-3 SU in their last 11 games on the road.
  • The total has gone UNDER in 4 of San Francisco’s last 5 games when playing on the road against Philadelphia.
  • San Francisco are 15-2 SU in their last 17 games against an opponent in the National Football Conference conference.
  • San Francisco are 6-1 ATS in their last 7 games against an opponent in the National Football Conference East division.
  • San Francisco are 6-1 ATS in their last 7 games played in December.
  • The total has gone UNDER in 4 of Philadelphia’s last 5 games when playing at home against San Francisco.
  • Philadelphia are 9-0 SU in their last 9 games against an opponent in the National Football Conference conference.
  • The total has gone UNDER in 6 of Philadelphia’s last 7 games against an opponent in the National Football Conference West division.
  • Philadelphia are 4-1-1 ATS in their last 6 games played on a Sunday.
  • Philadelphia are 4-1 ATS in their last 5 games when there was no favourite.


The following NFL betting lines are based on MyBookie Sportsbook.

Super Bowl Odds to Win this 2025 NFL Season

Teams Odds
San Francisco 49ers +550
Kansas City Chiefs +700
Baltimore Ravens +800
Buffalo Bills +1000
Detroit Lions+1200
Cincinnati Bengals +1300
Dallas Cowboys +1600
Philadelphia Eagles +1800
Miami Dolphins +2000
Green Bay Packers +2200
Houston Texans +2200
LA Chargers +2500
New York Jets +2500
Jacksonville Jaguars +3500
Los Angeles Rams +3500
Cleveland Browns +4000
Minnesota Vikings +4000
Atlanta Falcons +5000
Chicago Bears +5000
Indianapolis Colts +5000
Denver Broncos +7500
Las Vegas Raiders +7500
New Orleans Saints +7500
Pittsburgh Steelers +7500
Seattle Seahawks +7500
Tampa Bay Buccaneers +7500
Arizona Cardinals +10000
New England Patriots +15000
New York Giants +15000
Tennessee Titans +15000
Washington Commanders +15000
Carolina Panthers +25000

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