NFL Week 1 ATS Picks

NFL Week 1 ATS Picks

The National Football League has arrived. The games are ready to rock and roll.

The teams are getting their final preparations ready, and the action will be hot and heavy starting Thursday night. Then, the big Sunday slate hits, followed by Monday Night Football.

Let’s look at a few of our favorite games in Week 1. Here is a look at our Top 5 NFL Week 1 Against the Spread Picks.


NFL Week 1 ATS Picks | MyBookie Regular Season Preview

2023-24 NFL | 104th season of the National Football League
Regular Season: September 7, 2023 – January 7, 2024


Kansas City Chiefs vs. Detroit Lions | Thursday Night Football

ATS: -6.5
Thursday, September 7th, 2023 | NBC
GEHA Field at Arrowhead Stadium, Kansas City, MO

The defending Super Bowl Champions get the party started for Week 1 of the National Football League. This should be an excellent opportunity to get it going in Kansas City. Patrick Mahomes and company will get the banner raised, then put the Lions in their place early in the season.

Many folks are all over Detroit to compete and be an NFC contender. Before that, they must show they can hang with the big dogs. This game could have gone better for them. The Kansas City Chiefs win by 10+ in this game over the Detroit Lions on Thursday.

NFL Week 1 ATS Pick: -6.5 | Bet Chiefs at Lions
MyBookie Betting Lines for the Total


Chicago Bears vs. Green Bay Packers | NFC North Rivalry Game

ATS: -1
Sunday, September 10th, 2023 at 4:25 pm | CBS
Empower Field at Mile High, Denver, CO

A huge NFC North rivalry game. The Chicago Bears are at home against the Green Bay Packers. Justin Fields and company look to have a new roster ready to compete.

This is Year 3 for Fields, so many expect him to pick up his game. Several have put his name into the talk for National Football League Most Valuable Player.

Not sure we can go that far, but Fields and the Bears are better than Love and the Packers in this one. Look for Chicago to be rocking as they get a chance to beat a rivalry they rarely beat. Bears win this game at home.

NFL Week 1 ATS Pick: -1 | Bet Bears at Packers
MyBookie Betting Lines for the Total


Seattle Seahawks vs. Los Angeles Rams

ATS: -5.5
Sunday, September 10th, 2023 at 4:25 pm | FOX
Lumen Field, Seattle, WA

No Cooper Kupp will be a big-time problem for the Los Angeles Rams. Matthew Stafford has not been happy about the preseason, and that will boil over into the regular season.

The Seattle Seahawks were a fun team to watch a season ago, with Geno Smith playing good football. Do not be surprised if they start hot here. The Seahawks win this game and cover the spread at home over the Rams.

NFL Week 1 ATS Pick: -5.5 | Bet Seahawks at Rams
MyBookie Betting Lines for the Total


Jacksonville Jaguars at Indianapolis Colts

ATS: -5
Sunday, September 10th, 2023 at 1:00 pm | FOX
Lucas Oil Stadium, Indianapolis, IN

Trevor Lawrence and the Jacksonville Jaguars won a postseason game a season ago. People need to remember that when they are talking about the 2023 Jaguars. That team will be a season more experienced. This is going to be a fun team to follow.

On the other side, the Colts are an absolute mess. The Jonathan Taylor thing is terrible for the team and will not bode well in the win column. An already bad team got worse. Take the Jaguars to win this game on the road over the Colts.

NFL Week 1 ATS Pick: -5 | Bet Jaguars at Colts
MyBookie Betting Lines for the Total


Buffalo Bills at New York Jets | Monday Night Football

ATS: -2.5
Monday, September 11th, 2023 at 8:15 pm | ESPN, ESPN+, ABC
MetLife Stadium, East Rutherford, NJ

The final game of the Week 1 slate. Monday Night Football Live from the Meadowlands. The hype on this game is going to be out of control. Josh Allen and his Bills invade Aaron Rodgers and his new team – the Jets.

The Jets are getting much love with talk of them taking over the division. This would be a great start to that. But – not so sure it’s going actually to happen. Take the Buffalo Bills with their talent to win this game on the road. Buffalo -2.5!

NFL Week 1 ATS Pick: -2.5 | Bet Bills at Jets
MyBookie Betting Lines for the Total


NFL Week 1 Schedule

Dates: 9/7 – 9/11
BYE WEEK: No teams on bye

Date Spread Moneyline Over Under
Thu, Sept. 7 Lions at Chiefs (-7) Lions +232; Chiefs -300 54

Sun, Sept. 10

Texans at Ravens (-9.5)

Texans +330; Ravens -450


Sun, Sept. 10

Buccaneers at Vikings (-6.5)

Buccaneers +235; Vikings -300


Sun, Sept. 10

Bengals (-2.5) at Browns

Bengals -136; Browns +111


Sun, Sept. 10

Jaguars (-3) at Colts Jaguars -172; Colts +140 43.5

Sun, Sept. 10

49ers (-3) at Steelers 49ers -160; Steelers +130 40.5

Sun, Sept. 10

Cardinals at Commanders (-5.5) Cardinals +204; Commanders -259 40.5

Sun, Sept. 10

Titans at Saints (-3.5) Titans +150; Saints -185 41.5

Sun, Sept. 10

Panthers at Falcons (-3) Panthers +132; Falcons -162 42.5

Sun, Sept. 10

Eagles (-4.5) at Patriots Eagles -204; Patriots +164 45

Sun, Sept. 10

Dolphins at Chargers (-2.5) Dolphins +115; Chargers -141 50

Sun, Sept. 10

Packers at Bears (-2.5) Packers +114; Bears -139 44

Sun, Sept. 10

Rams at Seahawks (-5) Rams +185; Seahawks -232 47

Sun, Sept. 10

Raiders at Broncos (-3.5) Raiders +157; Broncos -194 44.5

Sun, Sept. 10

Cowboys (-3) at Giants Cowboys -168; Giants +136 46.5

Mon, Sept. 11

Bills (-1.5) at Jets Bills -121; Jets +100 47


The following NFL betting odds are based on MyBookie Sportsbook.

Super Bowl Odds to Win this 2025 NFL Season

The following NFL betting lines are based on MyBookie Sportsbook.

Teams Odds
San Francisco 49ers +550
Kansas City Chiefs +700
Baltimore Ravens +800
Buffalo Bills +1000
Detroit Lions +1200
Cincinnati Bengals +1300
Dallas Cowboys +1600
Philadelphia Eagles +1800
Miami Dolphins +2000
Green Bay Packers +2200
Houston Texans +2200
LA Chargers +2500
New York Jets +2500
Jacksonville Jaguars +3500
Los Angeles Rams +3500
Cleveland Browns +4000
Minnesota Vikings +4000
Atlanta Falcons +5000
Chicago Bears +5000
Indianapolis Colts +5000
Denver Broncos +7500
Las Vegas Raiders +7500
New Orleans Saints +7500
Pittsburgh Steelers +7500
Seattle Seahawks +7500
Tampa Bay Buccaneers +7500
Arizona Cardinals +10000
New England Patriots +15000
New York Giants +15000
Tennessee Titans +15000
Washington Commanders +15000
Carolina Panthers +25000

Bet Super Bowl Lines to Win

There you go. Those are our five favorite Week 1 Against the Spread Picks in the National Football League. We hope you enjoyed them and will get some bets in before the season kicks off. Best of luck, and enjoy the games!


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