NFL ATS Week 16: Expert Picks for Top Games You Can't Miss

With the NFL season at a critical juncture, NFL ATS Week 16 betting picks have never been more important. Week 16 is packed with high-stakes matchups that will shape playoff hopes, affect draft positioning, and set the momentum for the final stretch of the season. We’ve analyzed the key games, taking into account recent form, injuries, and matchup advantages to bring you the best against-the-spread picks for this week’s action.

Top ATS Picks for the Top Games NFL Week 16: Expert Bets to Watch
NFL Week 16 ATS Edge: Gain the Advantage Over the Competition

2024 NFL season | 104th season of National Football League in the United States
Week 16: Wednesday, December 25th – Monday, December 30th, 2024

Betting ATS Picks in the Sixteenth Week of the Season

The NFL season is reaching its most critical point, and Week 16 offers matchups that will determine playoff hopes, draft positioning, and momentu m heading into the final stretch.

We’ve analyzed the most compelling games, factoring in injuries, recent form, and matchup advantages to deliver the best against-the-spread bets for this week.

Here’s a breakdown of 10 top games and our ATS predictions.

Writer’s ATS Picks for the NFL Week 16

TNF: Broncos vs Chargers

Thursday, December 19th, 2024

Denver’s elite secondary poses a major challenge for Justin Herbert and the Chargers, who are short on playmakers outside of Ladd McConkey.

Combined with Denver’s strong run game, which has averaged 4.5 yards per carry recently, the Broncos can control the clock and rely on their defense to keep the game close.

The Chargers’ struggling run defense provides Denver with an edge to stay within the number.

NFL ATS Picks: Broncos +3

Texans vs Chiefs

Saturday, December 21st, 2024

The Texans‘ offense has hit a wall, averaging just 4.6 yards per play in recent weeks, and they face a stiff challenge against a Chiefs defense that has allowed only 18.2 points per game.

Whether Patrick Mahomes suits up or not, Kansas City’s defense is good enough to dictate the game.

Houston’s offensive line struggles and inefficiency on the road make the Chiefs a solid underdog bet.

NFL ATS Picks: Chiefs +2.5

Steelers vs Ravens

Saturday, December 21st, 2024

The Ravens’ defense has improved significantly, ranking in the top five in EPA since Week 11, while the Steelers’ offense remains inconsistent and inefficient.

Baltimore leads the NFL in net yards per play and boasts a balanced offense that can wear down Pittsburgh.

With a strong defense and home-field advantage, the Ravens are poised to cover the spread.

NFL ATS Picks: Ravens -6

Eagles vs Commanders

Sunday, December 22nd, 2024

The Eagles have emerged as the most complete team in the NFC, and their elite secondary will prove too much for Washington’s regressing offense.

Philadelphia dominated the Commanders earlier this season and should do so again, as Jayden Daniels has struggled against top-tier defenses.

Expect the Eagles’ balanced attack to win comfortably on the road.

NFL ATS Picks: Eagles -3.5

Rams vs Jets

Sunday, December 22nd, 2024

The Jets’ defense remains elite, ranking second in opponent pass yards per attempt, which presents a challenge for Matthew Stafford and the Rams’ pass-heavy offense.

New York has played its best football recently, ranking seventh in net yards per play over the last three weeks.

With Aaron Rodgers stabilizing the offense, the Jets can keep this game close at home.

NFL ATS Picks: Jets +3

Titans vs Colts

Sunday, December 22nd, 2024

Despite their poor record, the Titans rank higher than the Colts in net yards per play and have a defense capable of containing Anthony Richardson.

Tennessee’s pass rush will disrupt Richardson, who has struggled in recent weeks, and their offense should capitalize on a Colts defense that ranks in the bottom third of the league.

The Titans are a live underdog in this divisional matchup.

NFL ATS Picks: Titans +4.5

SNF: 49ers vs Dolphins

Sunday, December 22nd, 2024

The Dolphins’ offense, reliant on yards after the catch, faces a 49ers defense built to limit explosive plays and tackle in space.

Kyle Shanahan’s familiarity with Mike McDaniel’s scheme gives San Francisco a strategic edge, and their balanced attack remains one of the most efficient in the NFL.

The 49ers are a strong underdog with upset potential.

NFL ATS Picks: 49ers +1.5