NFL Week 11 Picks & Predictions | Expert Betting Insights

Since 2008, D.S. Williamson has written about sports and sports handicapping.

His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to sportsbook odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.

Carolina Panthers at Atlanta Falcons -3.5

Carolina was supposed to wallop the New Orleans Saints in NFL Week 10. Instead of destroying one of the worst teams in the NFL, the Panthers handed Kellen Moore and the Saints their second win of the season in a startling 13–9 loss.

On Sunday, the Carolina Panthers head to Atlanta to take on a desperate Atlanta Falcons team that was unlucky to lose to the Colts.

The ATL should have no trouble dominating a Panthers’ defense that made rookie QB Tyler Shough look like a veteran. Michael Penix Jr., Drake London, and Bijan Robinson lead Atlanta to a win and cover.

Writer’s Week 11 Pick: Falcons -3.5 (Bounce-Back Spot)

Panthers vs Falcons Betting Lines

Kansas City Chiefs -3.5 at Denver Broncos

Denver’s offense has struggled in recent games — but the Broncos keep finding ways to win.

The Denver Broncos took down both Houston and Las Vegas, but the Kansas City Chiefs are a much stronger opponent.

Still, Denver is an intriguing home underdog at +3.5 and worth a moneyline sprinkle. Sean Payton’s had extra prep time to fine-tune the offense, and Denver’s defense is tailor-made to frustrate Patrick Mahomes.

Give the Broncos a big shot on the moneyline.

Writer’s Week 11 Pick: Broncos +3.5 (Home Dog Value)

Chiefs vs Broncos Betting Lines

Detroit Lions at Philadelphia Eagles -1.5

Lions versus Eagles could define NFC playoff seeding — and the short-week setup favors Detroit.

The Philadelphia Eagles play this one just days after traveling to Green Bay for Monday Night Football, while the Detroit Lions come in rested and healthier on both sides of the ball.

Detroit’s defense looks rejuvenated, and Aidan Hutchinson is set to test the Eagles’ O-line protection. By kickoff, the Lions could be at full strength on offense — making the road moneyline attractive.

Writer’s Week 11 Pick: Lions Moneyline (Scheduling Edge)

Lions vs Eagles Betting Lines

Los Angeles Chargers -2.5 at Jacksonville Jaguars

Los Angeles continues to flirt with mediocrity — but this is a must-win game for their playoff hopes.

The Los Angeles Chargers face a Jacksonville Jaguars squad that’s been inconsistent at home, alternating strong defensive showings with costly turnovers.

If Justin Herbert finds rhythm early, Jacksonville’s secondary could get exposed. Expect LA to control tempo and squeak out a narrow cover on the road.

Writer’s Week 11 Pick: Chargers -2.5 (Must-Win Mentality)

Chargers vs Jaguars Betting Lines

D.S. Williamson’s Week 11 selections in the MyBookie Writers’ NFL Picks highlight value on scheduling edges, bounce-back spots, and situational betting angles across key AFC and NFC matchups. Follow the latest NFL betting odds and take advantage of early line movement before kickoff.

Henry is originally from Scotland but now resides in Metro Atlanta with his chef wife Penny.

As well as working as a Sports freelance writer, he also writes horror fiction.

Watson is the author of Karaoke Night, Crueller, and Off The Grid.

NFL Week 11 SU Picks

Let’s start with the Monday night game, where the Cowboys meet the struggling Raiders — and I’m backing Dallas to get it done.

The Dallas Cowboys have too much firepower for the Las Vegas Raiders to handle, especially with the latter’s offense sputtering late in games.

The Kansas City Chiefs had a bye week to regroup after losing to Buffalo — and Andy Reid’s squads tend to dominate coming off rest. Expect KC to take care of the Denver Broncos.

Finally, call it a hunch play — but I’m rolling with the Philadelphia Eagles to edge out the Detroit Lions in a potential playoff preview.

NFL Week 11 SU Picks

Cowboys vs Raiders – SU Pick: Cowboys
Chiefs vs Broncos – SU Pick: Chiefs
Eagles vs Lions – SU Pick: Eagles
Bet NFL Week 11 Odds

NFL Week 11 ATS Picks

Against the spread (ATS), I’m targeting lines where health, depth, and motivation all swing toward one side.

The New York Jets are dealing with injuries all over the roster — and the New England Patriots should take full advantage, covering the 11½-point spread with ease.

After falling to Miami, expect the Buffalo Bills to bounce back in a big way against the Tampa Bay Buccaneers, covering as 5½-point home favorites.

Meanwhile, the matchup between the Los Angeles Rams and Seattle Seahawks looks tight — but the Rams’ home-field edge gives them the edge to cover -2½.

NFL Week 11 ATS Picks

Patriots vs Jets – ATS Pick: Patriots -11.5
Bills vs Buccaneers – ATS Pick: Bills -5.5
Rams vs Seahawks – ATS Pick: Rams -2.5
Bet NFL Week 11 Lines

NFL Week 11 O/U Picks

Totals this week feature several contrasting tempos — from high-scoring shootouts to low-grind divisional duels.

The Tampa Bay Buccaneers tend to play in shootouts, and with the Buffalo Bills offense due to rebound, the OVER 47½ looks like the best bet.

Let’s double down on points for Monday night — the Las Vegas Raiders and Dallas Cowboys have enough offensive weapons to clear the 50½ total comfortably.

On the flip side, matchups between the Houston Texans and Tennessee Titans often lean low-scoring — the UNDER 39½ remains the smart side.

NFL Week 11 O/U Picks

Buccaneers vs Bills – Pick: OVER 47.5
Raiders vs Cowboys – Pick: OVER 50.5
Texans vs Titans – Pick: UNDER 39.5
Bet NFL Week 11 Totals

Henry Watkins’ Week 11 card in the MyBookie Writers’ NFL Picks blends high-confidence favorites, divisional totals, and value ATS angles for bettors chasing consistent returns across the NFL board. Stay updated with all the latest NFL betting odds before kickoff.