NFL Week 5 Parlay Picks Expert Analysis

The Seattle Seahawks take on the New York Giants on Monday Night Football. So, technically, we have yet to reach NFL Week 5 but that won’t keep us from writing down our top parlay plays.

Check out NFL lines for 2-team, 3-team, and 4-team NFL Week 5 ATS and SU parlay picks.

2023 NFL Week 5 Parlay Picks | MyBookie Regular Season Preview

2023-24 NFL | 104th season of the National Football League
NFL Week 5: Thursday, October 5th – Monday, October 10th, 2023

NFL Week 5 ATS Parlay Picks

2-Team Parlay Pick

Jacksonville Jaguars at Buffalo Bills -5.5
New York Giants at Miami Dolphins -9.5

Even if the line rises, which it likely will, the Buffalo Bills should cover. Josh Allen and his mates are playing like the best team in the NFL. Buffalo’s D held Miami to 20 points in an unbelievable 48-20 Bills’ victory. The only team that appears capable of hanging with Buffalo is San Francisco. Jacksonville is not San Francisco.

Miami fell to the Bills, but they have a couple of excuses. First, it was impossible for the Dolphins not to bounce after scoring 70 points against Denver in NFL Week 3. Second, the Fins faced arguably the best team in the NFL.

On Sunday, Miami takes on the New York Giants who shouldn’t play starting left tackle Andrew Thomas and starting running back Saquon Barkley. At least 1 figures to sit on the bench. Not only that, but Miami is at home.

2-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

3-Team ATS Parlay Pick

Jacksonville Jaguars at Buffalo Bills -5.5
New York Giants at Miami Dolphins -9.5
Carolina Panthers at Detroit Lions -8.5

Detroit’s 34-20 victory over the Green Bay Packers at Lambeau is the type of victory that should catapult the Lions into the elite team category. Detroit will have zero issues covering a high spread against a Panthers‘ team without their two top defenders in Shaq Thompson and Xavier Woods.

3-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

4-Team ATS Parlay Pick

Jacksonville Jaguars at Buffalo Bills -5.5
New York Giants at Miami Dolphins -9.5
Carolina Panthers at Detroit Lions -8.5
Dallas Cowboys at San Francisco 49ers -3.5

For sure, the Dallas Cowboys are an elite NFL squad. But San Francisco might be the best team in the league. The 49ers run an offense that makes it easy to get the ball to Deebo Samuel, George Kittle, and Christian McCaffrey. Then if you bottle up those three, Brock Purdy will throw to Brandon Ayuik. SF covers. 

4-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

2-Team Parlay Money Line Pick

Philadelphia Eagles at Los Angeles Rams +172
Cincinnati Bengals at Arizona Cardinals +150

The Eagles were lucky to beat the Commanders. Philly’s defensive line is great but their linebackers and secondary have struggled this season. Matthew Stafford will throw to Puca Nacua and Tyler Higbee in the middle of the field. Kyren Williams will be in the mix because he’s a good pass-catching running back.

Cincinnati is a mess. Arizona is much better than people had given them credit for being. So AZ, because this happens in the desert, should send the Bengals to 1-4.  

2-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

3-Team Parlay Money Line Pick

Philadelphia Eagles at Los Angeles Rams +172
Cincinnati Bengals at Arizona Cardinals +150
New Orleans Saints -102 at New England Patriots

Patriots versus Saints is an even game. New England could be without their top two starting cornerbacks, Christian Gonzalez and Jonathan Jones. If neither Jones nor Gonzalez plays, Derek Carr should break out with his best game as a Saint.

3-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

4-Team Parlay Money Line Pick

Philadelphia Eagles at Los Angeles Rams +172
Cincinnati Bengals at Arizona Cardinals +150
New Orleans Saints -102 at New England Patriots
Green Bay Packers at Las Vegas Raiders -101

Backing Green Bay will gain momentum for sure. However, Raiders starter Aidan O’Connell wasn’t horrible. The thing is O’Connell got sacked 7 times. So without those 7 sacks, he would have posted much better stats.

If O’Connell doesn’t start, Garoppolo will. The game happens in Vegas. So the Raiders have an edge.   

4-Team Picks | NFL Week 5 Parlay Picks
MyBookie Betting Lines for the Games

The following NFL betting odds are based on MyBookie Sportsbook.

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