NFL Week 9 Picks, Predictions & Betting Odds — Expert MyBookie Breakdown

Since 2008, D.S. Williamson has written about sports and sports handicapping.

His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to sportsbook odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.

Chicago Bears -2.5 at Cincinnati Bengals

The Bengals are coming off a wild 39–38 loss to the Jets — but the offense showed real life with Joe Flacco under center.

The Cincinnati Bengals proved they can move the ball with efficiency, even in defeat. But their defense collapsed late, costing them a crucial win.

The Chicago Bears remain a tough team to trust — especially on the road.

Unless their defense generates turnovers, they can’t stop much.

Rookie QB Caleb Williams continues to make risky throws under pressure.

This is a bounce-back spot for Cincy at home.

The Bengals are the right moneyline play.

Writer’s Week 9 Pick: Bengals Moneyline (Bounce-Back Spot)

Bears vs Bengals Betting Lines

Indianapolis Colts -3.5 at Pittsburgh Steelers

The Steelers defense got shredded last week — and the matchup doesn’t get any easier against Indianapolis.

The Pittsburgh Steelers allowed Green Bay TE Tucker Kraft to post 143 yards and 2 TDs. Now they face Colts QB Daniel Jones, who loves targeting his tight ends, especially Tyler Warren.

Even if Pittsburgh shifts coverage, they’ll have to deal with Jonathan Taylor — one of the NFL’s most dangerous backs.

Indy’s offensive balance and Pittsburgh’s regression make this one-sided. The Colts roll to another win and cover.

Writer’s Week 9 Pick: Colts -3.5 (Confident Cover)

Colts vs Steelers Betting Lines

San Francisco 49ers -2.5 at New York Giants

The Giants’ offense faces a huge challenge after losing rookie star Cam Skattebo to a season-ending ankle injury.

Without Skattebo, the New York Giants may struggle to establish the run.

Backup Tyrone Tracey is capable, and QB Jaxon Dart remains steady — but the loss of Skattebo limits their explosive potential.

The San Francisco 49ers could also be shorthanded, with Brock Purdy, Ricky Pearsall, and DE Bryce Huff all questionable.

Given those injuries, this one feels ripe for an upset.

Giants steal it straight up at home.

Writer’s Week 9 Pick: Giants Moneyline (Upset Alert)

49ers vs Giants Betting Lines

Kansas City Chiefs -1.5 at Buffalo Bills

This matchup has all the makings of an instant classic — but Buffalo may finally be turning the corner defensively.

Before Week 8, many expected the Kansas City Chiefs to march into Buffalo and dominate. But the Buffalo Bills defense looked rejuvenated last week, holding Carolina in check while Josh Allen and the offense exploded for 40 points.

Yes, Andy Dalton isn’t Patrick Mahomes — but Buffalo has historically matched up well against KC in regular-season play.

This feels like another home statement game for the Bills.

Back Buffalo on the moneyline.

Writer’s Week 9 Pick: Bills Moneyline (Home Edge)

Chiefs vs Bills Betting Lines

D.S. Williamson’s Week 9 selections in the MyBookie Writers’ NFL Picks lean on momentum, matchup analytics, and situational edges — offering data-backed insights for bettors targeting NFL betting odds, ATS lines, and moneyline plays with real value before kickoff.

Henry is originally from Scotland but now resides in Metro Atlanta with his chef wife Penny.

As well as working as a Sports freelance writer, he also writes horror fiction.

Watson is the author of Karaoke Night, Crueller, and Off The Grid.

NFL Week 9 SU Picks

Looking to build a winning parlay ticket? For my straight-up (SU) plays this weekend, I’m locking in a trio of safer picks that still carry solid betting value.

The Green Bay Packers should handle business against the Carolina Panthers — Green Bay’s ground game and balance on offense give them the edge here.

Divisional matchups are always tough, but I’m on the Detroit Lions to take care of the Minnesota Vikings at home.

Finally, the Baltimore Ravens look like they’re back in rhythm and should have no trouble rolling past the Miami Dolphins.

NFL Week 9 SU Picks

Packers vs Panthers – SU Pick: Packers
Lions vs Vikings – SU Pick: Lions
Ravens vs Dolphins – SU Pick: Ravens
Bet NFL Week 9 Odds

NFL Week 9 ATS Picks

Against the spread (ATS), I’m focusing on matchups where the market hasn’t fully adjusted to form and momentum.

After a strong start to the season, the Pittsburgh Steelers are trending down — and the Indianapolis Colts should capitalize. I’m taking Indy to cover -3.

The Dallas Cowboys vs Arizona Cardinals line is tight for a reason, but I trust Dallas to get it done and cover -2½.

Finally, I’m backing the Seattle Seahawks at home against the Washington Commanders — Seattle should protect the house and cover -3½.

NFL Week 9 ATS Picks

Steelers vs Colts – ATS Pick: Colts -3
Cowboys vs Cardinals – ATS Pick: Cowboys -2.5
Seahawks vs Commanders – ATS Pick: Seahawks -3.5
Bet NFL Week 9 Lines

NFL Week 9 O/U Picks

Totals betting is all about tempo and matchups — and this Week 9 board delivers several high-value opportunities.

Whenever the Kansas City Chiefs and Buffalo Bills meet, fireworks follow.

Expect another shootout and take the OVER 52½.

In the Cowboys vs Cardinals matchup, both teams can move the ball, but red-zone execution has been inconsistent — I’m leaning UNDER 54.

And for a defensive grinder, the Denver Broncos vs Houston Texans looks like a slugfest — UNDER 39½ feels right.

NFL Week 9 O/U Picks

Chiefs vs Bills – Pick: OVER 52.5
Cowboys vs Cardinals – Pick: UNDER 54
Broncos vs Texans – Pick: UNDER 39.5
Bet NFL Week 9 Totals

Henry Watkins’ Week 9 card in the MyBookie Writers’ NFL Picks combines confident favorites with sharp underdog and total plays — ideal for bettors chasing value on spreads, totals, and parlays in Week 9. Get your sportsbook login ready and lock in your bets early to beat the line movement.