Chiefs vs 49ers Pick: 2024 NFL Week 7 SB Rematch Game

Week 7 of the NFL season brings a highly anticipated Super Bowl rematch as the Kansas City Chiefs visit the San Francisco 49ers—one of the most important games of the regular season, making it a prime opportunity for NFL bets today.

Chiefs vs 49ers Pick for the 2024 NFL Week 7 Rematch Game
Must-Read: Expert Analysis Points to Surprising Winner in Chiefs vs. 49ers

2024 NFL Season | 104th season of National League in the United States
Week 7: Thursday, October 17th – Monday, October 21st, 2024

Betting 2024 Kansas City Chiefs at San Francisco 49ers Week 7 Game

Week 7 of the NFL is here, and one of the biggest matchups of the week is the Kansas City Chiefs traveling to California to face the San Francisco 49ers.

This is a rematch of last year’s Super Bowl, which was won by the Chiefs in an overtime finish.

Both teams started this season as two of the top squads in the league, and this game could be a preview of another Super Bowl showdown.

The Chiefs are the last undefeated team in the league, while the 49ers are looking to get back on track after some early-season struggles.

This game is set for Sunday at Levi’s Stadium, and the action kicks off at 4:25 p.m. ET.

It’s expected to be a close game, and many eyes will be watching to see if the 49ers can avenge their Super Bowl loss.

NFL Week 7: Kansas City Chiefs at San Francisco 49ers
Sunday, October 20th, 2024 at 4:25 PM FOX | Levi’s Stadium, Santa Clara, CA

ATS Odds: San Francisco -1
Money line Odds: Chiefs -106 / 49ers -116
Over/Under Odds: 47

Writer’s Breakdown and Pick for the Chiefs vs 49ers Game

Chiefs Ready to Stay Undefeated

The Kansas City Chiefs have been one of the best teams in the NFL all season.

They are 5-0 heading into this game and have now won 11 straight games dating back to last year.

Head coach Andy Reid has an amazing record after bye weeks, winning 21 out of 24 games in this situation.

Reid and quarterback Patrick Mahomes have also dominated the 49ers in the past, winning all four matchups, including two Super Bowl.

The Chiefs had a slow start to the season with some close wins, but they had their best game in Week 6 against the New Orleans Saints.

The Chiefs dominated the Saints, gaining over double the yards and first downs.

Patrick Mahomes threw for a season-high in yards, while Travis Kelce had a big game, and Kareem Hunt rushed for over 100 yards.

The Chiefs’ defense has also been great, allowing the sixth-fewest points in the league.

While the offense was inconsistent in the first few games, the defense carried the team.

With key players Rashee Rice and Isiah Pacheco still injured, Mahomes and Reid will need to continue making adjustments on offense to keep up the winning streak.

49ers Trying to Get Back on Track

The San Francisco 49ers started the season with a big win over the New York Jets but then hit a rough patch, losing three out of their next four games.

The team has dealt with injuries to key players like Christian McCaffrey and Deebo Samuel, which has made it difficult to find consistency on offense.

McCaffrey still hasn’t played this season, but the 49ers hope to have Samuel back to full strength against the Chiefs.

Quarterback Brock Purdy has stepped up despite the injuries around him.

Purdy is no longer just managing the game; he’s making big plays and ranks near the top of the league in passing yards.

The 49ers’ offense is still one of the best in the NFL, and with Deebo Samuel and George Kittle healthy, they have plenty of firepower to challenge the Chiefs’ defense.

Defensively, the 49ers have been up and down, but they’ve shown they can be tough against top offenses.

This game will be a big test for their defense, especially with Patrick Mahomes on the other side.

The 49ers need to limit the Chiefs’ explosive plays if they want to have a chance to win this game.

Betting Odds and What to Expect

The betting lines are tight for this game.

The 49ers are favored by just 1.5 points, and the total for the game is set at 47 points.

The Chiefs are listed as slight underdogs at +1.5, but they have a great track record in close games and have the momentum of being undefeated.

Both teams have strong offenses, but the defenses will be key in this matchup.

The Chiefs’ defense has been one of the best in the league, while the 49ers have struggled at times, especially in close games.

With both teams likely to put points on the board, the over/under line will be an interesting one to watch.

Key Players to Watch

Patrick Mahomes (Chiefs):
Mahomes has been a star once again this season, leading the Chiefs to an undefeated record.
He’s coming off his best game of the season and will need to be at his best to beat a tough 49ers defense.
Travis Kelce (Chiefs):
Kelce is always a key target for Mahomes, and he’s been a big reason for the Chiefs’ success.
Look for him to have another big game as he looks to exploit the 49ers’ secondary.
Brock Purdy (49ers):
Purdy has shown that he can lead the 49ers’ offense, even without some of his key weapons.
He’ll need to play well and make smart decisions to give his team a chance to win.
Deebo Samuel (49ers):
Samuel is a game-changer for the 49ers, and his return to full health is huge for this game.
If he can make some big plays, it could be the difference in the outcome.

Prediction: 49ers Win a Close Game

This game has all the makings of a classic, with two of the best teams in the NFL going head-to-head.

While the Chiefs have looked unstoppable this season, the 49ers are getting healthy and playing at home, which gives them an edge.

Our prediction is that the 49ers will come out on top in a close game.

The 49ers have all of their key offensive players back, and they will be able to take advantage of a Chiefs defense that has shown some weaknesses against good passing attacks.

Look for Brock Purdy and Deebo Samuel to make big plays and lead the 49ers to a 27-24 victory.

The key to this game will be the play of both quarterbacks.

Patrick Mahomes has been great all season, and Brock Purdy has stepped up for the 49ers.

If the 49ers’ defense can limit the Chiefs’ big plays and take advantage of their home-field advantage, they should be able to come away with the win.

NFL Week 7 SU Pick: San Francisco 49ers -116

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Kansas City at San Francisco Betting Trends Today

Brock Purdy has gone over 254.5 pass yards in four of his last five games
Patrick Mahomes has won six straight games as an underdog.
Kansas City is 9-1-1 ATS in their last 11 games and 10-0 SU in its last 10 games
San Francisco is 3-7 ATS in its last 10 games
The total has gone UNDER in 8 of Kansas City’s last 12 games
UNDER is 3-2 in the Chiefs’ games this season.
The total has gone OVER in 6 of San Francisco’s last 8 games
OVER is 4-2 in the 49ers’ games this season.
San Francisco is 12-6 SU in its last 18 games
Chiefs are 4-1 against the spread this season.
49ers are 3-3 against the spread this season.