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NFL Football Lines Week Thirteen
Top NFL Week 13 Matchups to Watch
2025 NFL Season | 106th season of the National Football League
Week 13: Thursday, November 27th – Monday, December 1st, 2025
BYE WEEK: No teams on bye.
Key Games to Watch and Bet
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NFL Football Lines Week Thirteen
Betting 2025 NFL Week 13 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change
Nov 27 – Totals 49
Packers Spread +2.5, Winner +122
Lions Spread -2.5, Winner -150
Nov 27 – Totals O/U 52
Chiefs Spread -3.5, Winner -180
Cowboys Spread +3.5, Winner +145
Nov 27 – Totals O/U 51.5
Bengals Spread +7, Winner +251
Ravens Spread -7, Winner -325
Nov 28 – Totals 44
Bears Spread +7, Winner +242
Eagles Spread -7, Winner -310
Nov 30 – Totals 45
Rams Spread -10.5, Winner -649
Panthers Spread +10.5, Winner +420
Nov 30 – Totals 37.5
49ers Spread -5, Winner -250
Browns Spread +5, Winner +190
Nov 30 – Totals O/U 45
Cardinals Spread +3, Winner +131
Buccaneers Spread -3, Winner -168
Nov 30 – Totals O/U 44.5
Texans Spread +4.5, Winner +178
Colts Spread -4.5, Winner -234
Nov 30 – Totals O/U 42
Jaguars Spread -6.5, Winner -325
Titans Spread +6.5, Winner +234
Nov 30 – Totals O/U 39.5
Falcons Spread -2.5, Winner -149
Jets Spread +2.5, Winner +117
Nov 30 – Totals O/U 42
Saints Spread +6, Winner +210
Dolphins Spread -6, Winner -280
Nov 30 – Totals O/U 41
Vikings Spread +10.5, Winner +450
Seahawks Spread -10.5, Winner -725
Nov 30 – Totals O/U 41
Raiders Spread +9.5, Winner +360
Chargers Spread -9.5, Winner -526
Nov 30 – Totals O/U 47.5
Bills Spread -3.5, Winner -199
Steelers Spread +3.5, Winner +153
Nov 30 – Totals O/U 43.5
Broncos Spread -6.5, Winner -300
Commanders Spread +6.5, Winner +224
Dec 1 – Totals O/U 46.5
Giants Spread +7, Winner +292
Patriots Spread -7, Winner -415
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About the Author
- D.S. Williamson
- Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.
