Explore the NFL top betting Week 13 odds at MyBookie for insights, strategies and updates to enhance your game day experience.
NFL Football Lines Week Thirteen
Top NFL Week 13 Matchups to Watch
2025 NFL Season | 106th season of the National Football League
Week 13: Thursday, November 27th – Monday, December 1st, 2025
BYE WEEK: No teams on bye.
Key Games to Watch and Bet
So, what are you waiting for?
Head over to our NFL betting lines now and Sign Up for an Account to bet on all the matchups of Week 13 and the rest of the season, you’re sure to find the perfect wager to add some extra excitement to your NFL viewing experience!
NFL Football Lines Week Thirteen
Betting 2025 NFL Week 13 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change
| Date | Spread | Moneyline | Over Under |
|---|---|---|---|
| Thu, Nov. 27, 1:00 PM EST | Packers at Lions | Packers TBA; Lions TBA | TBA |
| Thu. Nov. 27, 4:30 PM EST | Chiefs vs Cowboys | Chiefs TBA; Cowboys TBA | TBA |
| Thu, Nov. 27, 8:20 PM EST | Bengals at Ravens | Bengals TBA; Ravens TBA | TBA |
| Fri. Nov. 28, 3:00 PM EST | Bears at Eagles | Bears TBA; Eagles TBA | TBA |
| Sun. Nov. 30, 1:00 PM EST | Rams at Panthers | Rams TBA; Panthers TBA | TBA |
| Sun, Nov. 30, 1:00 PM EST | 49ers at Browns | 49ers TBA; Browns TBA | TBA |
| Sun. Nov. 30, 1:00 PM EST | Texans at Colts | Texans TBA; Colts TBA | TBA |
| Sun, Nov. 30, 1:00 PM EST | Saints at Dolphins | Saints TBA; Dolphins TBA | TBA |
| Sun. Nov. 30, 1:00 PM EST | Falcons at Jets | Falcons TBA; Jets TBA | TBA |
| Sun, Nov. 30, 1:00 PM EST | Cardinals at Buccaneers | Cardinals TBA; Buccaneers TBA | TBA |
| Sun. Nov. 30, 1:00 PM EST | Jaguars at Titans | Jaguars TBA; Titans TBA | TBA |
| Sun, Nov. 30, 4:05 PM EST | Vikings at Seahawks | Vikings TBA; Seahawks TBA | TBA |
| Sun. Nov. 30, 4:25 PM EST | Raiders at Chargers | Raiders TBA; Chargers TBA | TBA |
| Sun, Nov. 30, 4:25 PM EST | Bills at Steelers | Bills TBA; Steelers TBA | TBA |
| Sun, Nov, 30, 8:20 PM EST | Broncos at Commanders | Broncos TBA; Commanders TBA | TBA |
| Mon. Dec. 1, 8:15 PM EST | Giants at Patriots | Giants TBA; Patriots TBA | TBA |
<< Week Twelve
Elevate your NFL Season with MyBookie + Loyalty Rewards Program
Start to earn points with the Sportsbook and Casino Loyalty Program to level up, get exclusive bonuses and rakeback in every stage of the 2025/26 Season: Draft, Offseason, Preseason, Regular Season, Playoffs and Super Bowl.
Join the MyBookie program, subscribing will guarantee your share of $15,000 in free plays.
Bet On NFL top betting odds, anywhere, anytime
NFL Betting News
Complement your betting plans with NFL betting news, rumors, trends and everything you need to know for the 2025/26 NFL season that comes loaded with opportunities to win with top teams in all Divisions, Conferences AFC, NFC and the Super Bowl.
All NFL Teams to Win
AFC
About the Author
- D.S. Williamson
- Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.
