Explore the NFL top betting Week 18 odds at MyBookie for insights, strategies and updates to enhance your game day experience.
NFL Football Lines Week Eighteen
Top NFL Week 18 Matchups to Watch
2025 NFL Season | 106th season of the National Football League
Week 18: Schedule TBD
BYE WEEK: No teams on bye.
Key Games to Watch and Bet
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NFL Football Lines Week Eighteen
Betting 2025 NFL Week 18 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change
Jan 3 – Totals O/U 44
Panthers Spread +2.5, Winner +114
Buccaneers Spread -2.5, Winner -145
Jan 3 – Totals O/U 49.5
Seahawks Spread -1, Winner -120
49ers Spread +1, Winner -106
Jan 4 – Totals 44
Saints Spread +3.5, Winner +145
Falcons Spread -3.5, Winner -187
Jan 4 – Totals O/U 51.5
Cowboys Spread -4, Winner -206
Gints Spread +4, Winner +159
Jan 4 – Totals 44.5
Browns Spread +7.5, Winner +285
Bengals Spread -7.5, Winner -400
Jan 4 – Totals 39
Colts Spread +10.5, Winner +430
Texans Spread -10.5, Winner -676
Jan 4 – Totals O/U 47.5
Titans Spread +12.5, Winner +500
Jaguars Spread -12.5, Winner -847
Jan 4 – Totals O/U 36.5
Packers Spread +6.5, Winner +226
Vikings Spread -6.5, Winner -310
Jan 4 – Totals 37.5
Chargers Spread +13, Winner +600
Broncos Spread -13, Winner -1099
Jan 4 – Totals O/U 45.5
Dolphins Spread +10.5, Winner +420
Patriots Spread -10.5, Winner -649
Jan 4 – Totals O/U 37
Chiefs Spread -5.5, Winner -260
Raiders Spread +5.5, Winner +197
Jan 4 – Totals O/U 50.5
Lions Spread +3, Winner +134
Bears Spread -3, Winner -172
Jan 4 – Totals O/U 38
Jets Spread +7, Winner +285
Bills Spread -7, Winner -400
Jan 4 – Totals O/U 41
Commanders Spread +7, Winner +260
Eagles Spread -7, Winner -360
Jan 4 – Totals O/U 46
Cardinals Spread +7, Winner +270
Rams Spread -7, Winner -370
Jan 4 – Totals O/U 41
Ravens Spread -3.5, Winner -206
Steelers Spread +3.5, Winner +159
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About the Author
- D.S. Williamson
- Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.
