NFL Top Betting Week 12 Odds: Which teams are favored in this week?

Written by on August 1, 2025

Get your NFL top betting Week 12 odds at MyBookie for insights, strategies and updates to enhance your game day experience.

 

NFL Football Lines Week Twelve
Top NFL Week 12 Matchups to Watch

2025 NFL Season | 106th season of the National Football League
Week 12: Thursday, November 20th – Monday, November 24th, 2025
BYE WEEK: Broncos, Chargers, Dolphins, Commanders

 

Key Games to Watch and Bet

So, what are you waiting for?
Head over to our NFL betting lines now and Sign Up for an Account to bet on all the matchups of Week 12 and the rest of the season, you’re sure to find the perfect wager to add some extra excitement to your NFL viewing experience!

 
NFL Bonus
NFL top betting Week 12 odds

 
 

NFL Football Lines Week Twelve

Betting 2025 NFL Week 12 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change

Nov 20 – Totals TBA
Bills Spread TBA, Winner TBA
Texans Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Jets Spread TBA, Winner TBA
Ravens Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Steelers Spread TBA, Winner TBA
Bears Spread TBA, Winner TBA

Nov 23 – Totals TBA
Patriots Spread TBA, Winner TBA
Bengals Spread TBA, Winner TBA

Nov 23 – Totals TBA
Giants Spread TBA, Winner TBA
Lions Spread TBA, Winner TBA

Nov 23 – Totals TBA
Vikings Spread TBA, Winner TBA
Packers Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Colts Spread TBA, Winner TBA
Chiefs Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Seahawks Spread TBA, Winner TBA
Titans Spread TBA, Winner TBA

Nov 23 – Totals O/U 48.236
Jaguars Spread TBA, Winner TBA
Cardinals Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Browns Spread TBA, Winner TBA
Raiders Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Eagles Spread TBA, Winner TBA
Cowboys Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Falcons Spread TBA, Winner TBA
Saints Spread TBA, Winner TBA

Nov 23 – Totals O/U TBA
Buccaneers Spread TBA, Winner TBA
Rams Spread TBA, Winner TBA

Nov 24 – Totals O/U TBA
Panthers Spread TBA, Winner TBA
49ers Spread TBA, Winner TBA

 

Elevate your NFL Season with MyBookie + Loyalty Rewards Program

Start to earn points with the Sportsbook and Casino Loyalty Program to level up, get exclusive bonuses and rakeback in every stage of the 2025/26 Season: Draft, Offseason, Preseason, Regular Season, Playoffs and Super Bowl.

Join the MyBookie program, subscribing will guarantee your share of $15,000 in free plays.

Bet On NFL top betting odds, anywhere, anytime

 

NFL Betting News

Complement your betting plans with NFL betting news, rumors, trends and everything you need to know for the 2025/26 NFL season that comes loaded with opportunities to win with top teams in all Divisions, Conferences AFC, NFC and the Super Bowl.

 
 

All NFL Teams to Win

 
 
 

About the Author

MyBookie's Expert Writer
  • D.S. Williamson
  • Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.