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AFC Conference Betting: Top Odds and Insights | MyBookie

Oct 6 06:20 PM

NFL - AFC Conference - Winner

NFL - Futures - NFL - AFC Conference - Winner

Oct 6 06:20 PM

NFL - AFC West - Division Winner (reg. season)

NFL - Futures - NFL - AFC West - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - AFC East - Division Winner (reg. season)

NFL - Futures - NFL - AFC East - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - AFC North - Division Winner (reg. season)

NFL - Futures - NFL - AFC North - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - AFC South - Division Winner (reg. season)

NFL - Futures - NFL - AFC South - Division Winner (reg. season)
2025 - 09 - 15 17:00+00:00
2025 - 09 - 15 18:00+00:00
Tampa + Bay Events Postal Address
Real time odds for Tampa Bay Buccaneers and Houston Texans and the rest of 2025 - 09 - 15 17:00+00:00 games.
Tampa Bay Buccaneers v Houston Texans

Sep 15 05:00 PM

Spread

Winner

Total

team-logo Houston Texans

team-logo Tampa Bay Buccaneers

2025 - 09 - 15 20:00+00:00
2025 - 09 - 15 21:00+00:00
Los + Angeles Events Postal Address
Real time odds for Los Angeles Chargers and Las Vegas Raiders and the rest of 2025 - 09 - 15 20:00+00:00 games.
Los Angeles Chargers v Las Vegas Raiders

Sep 15 08:00 PM

Spread

Winner

Total

team-logo Las Vegas Raiders

team-logo Los Angeles Chargers

2025 - 09 - 18 18:15+00:00
2025 - 09 - 18 19:15+00:00
Miami + Dolphins Events Postal Address
Real time odds for Miami Dolphins and Buffalo Bills and the rest of 2025 - 09 - 18 18:15+00:00 games.
Miami Dolphins v Buffalo Bills

Sep 18 06:15 PM

Spread

Winner

Total

team-logo Buffalo Bills

team-logo Miami Dolphins

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Los + Angeles Events Postal Address
Real time odds for Los Angeles Rams and Philadelphia Eagles and the rest of 2025 - 09 - 21 11:00+00:00 games.
Los Angeles Rams v Philadelphia Eagles

Sep 21 11:00 AM

Spread

Winner

Total

team-logo Philadelphia Eagles

team-logo Los Angeles Rams

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Atlanta + Falcons Events Postal Address
Real time odds for Atlanta Falcons and Carolina Panthers and the rest of 2025 - 09 - 21 11:00+00:00 games.
Atlanta Falcons v Carolina Panthers

Sep 21 11:00 AM

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Winner

Total

team-logo Carolina Panthers

team-logo Atlanta Falcons

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Houston + Texans Events Postal Address
Real time odds for Houston Texans and Jacksonville Jaguars and the rest of 2025 - 09 - 21 11:00+00:00 games.
Houston Texans v Jacksonville Jaguars

Sep 21 11:00 AM

Spread

Winner

Total

team-logo Jacksonville Jaguars

team-logo Houston Texans

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Las + Vegas Events Postal Address
Real time odds for Las Vegas Raiders and Washington Commanders and the rest of 2025 - 09 - 21 11:00+00:00 games.
Las Vegas Raiders v Washington Commanders

Sep 21 11:00 AM

Spread

Winner

Total

team-logo Washington Commanders

team-logo Las Vegas Raiders

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Pittsburgh + Steelers Events Postal Address
Real time odds for Pittsburgh Steelers and New England Patriots and the rest of 2025 - 09 - 21 11:00+00:00 games.
Pittsburgh Steelers v New England Patriots

Sep 21 11:00 AM

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Winner

Total

team-logo New England Patriots

team-logo Pittsburgh Steelers

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Indianapolis + Colts Events Postal Address
Real time odds for Indianapolis Colts and Tennessee Titans and the rest of 2025 - 09 - 21 11:00+00:00 games.
Indianapolis Colts v Tennessee Titans

Sep 21 11:00 AM

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Winner

Total

team-logo Tennessee Titans

team-logo Indianapolis Colts

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Green + Bay Events Postal Address
Real time odds for Green Bay Packers and Cleveland Browns and the rest of 2025 - 09 - 21 11:00+00:00 games.
Green Bay Packers v Cleveland Browns

Sep 21 11:00 AM

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Winner

Total

team-logo Cleveland Browns

team-logo Green Bay Packers

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
Cincinnati + Bengals Events Postal Address
Real time odds for Cincinnati Bengals and Minnesota Vikings and the rest of 2025 - 09 - 21 11:00+00:00 games.
Cincinnati Bengals v Minnesota Vikings

Sep 21 11:00 AM

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Winner

Total

team-logo Minnesota Vikings

team-logo Cincinnati Bengals

2025 - 09 - 21 11:00+00:00
2025 - 09 - 21 12:00+00:00
New + York Events Postal Address
Real time odds for New York Jets and Tampa Bay Buccaneers and the rest of 2025 - 09 - 21 11:00+00:00 games.
New York Jets v Tampa Bay Buccaneers

Sep 21 11:00 AM

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Winner

Total

team-logo Tampa Bay Buccaneers

team-logo New York Jets

2025 - 09 - 21 14:05+00:00
2025 - 09 - 21 15:05+00:00
New + Orleans Events Postal Address
Real time odds for New Orleans Saints and Seattle Seahawks and the rest of 2025 - 09 - 21 14:05+00:00 games.
New Orleans Saints v Seattle Seahawks

Sep 21 02:05 PM

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Winner

Total

team-logo Seattle Seahawks

team-logo New Orleans Saints

2025 - 09 - 21 14:05+00:00
2025 - 09 - 21 15:05+00:00
Denver + Broncos Events Postal Address
Real time odds for Denver Broncos and Los Angeles Chargers and the rest of 2025 - 09 - 21 14:05+00:00 games.
Denver Broncos v Los Angeles Chargers

Sep 21 02:05 PM

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Winner

Total

team-logo Los Angeles Chargers

team-logo Denver Broncos

2025 - 09 - 21 14:25+00:00
2025 - 09 - 21 15:25+00:00
Dallas + Cowboys Events Postal Address
Real time odds for Dallas Cowboys and Chicago Bears and the rest of 2025 - 09 - 21 14:25+00:00 games.
Dallas Cowboys v Chicago Bears

Sep 21 02:25 PM

Spread

Winner

Total

team-logo Chicago Bears

team-logo Dallas Cowboys

2025 - 09 - 21 14:25+00:00
2025 - 09 - 21 15:25+00:00
Arizona + Cardinals Events Postal Address
Real time odds for Arizona Cardinals and San Francisco 49ers and the rest of 2025 - 09 - 21 14:25+00:00 games.
Arizona Cardinals v San Francisco 49ers

Sep 21 02:25 PM

Spread

Winner

Total

team-logo San Francisco 49ers

team-logo Arizona Cardinals

2025 - 09 - 21 18:20+00:00
2025 - 09 - 21 19:20+00:00
Kansas + City Events Postal Address
Real time odds for Kansas City Chiefs and New York Giants and the rest of 2025 - 09 - 21 18:20+00:00 games.
Kansas City Chiefs v New York Giants

Sep 21 06:20 PM

Spread

Winner

Total

team-logo New York Giants

team-logo Kansas City Chiefs

2025 - 09 - 22 18:15+00:00
2025 - 09 - 22 19:15+00:00
Detroit + Lions Events Postal Address
Real time odds for Detroit Lions and Baltimore Ravens and the rest of 2025 - 09 - 22 18:15+00:00 games.
Detroit Lions v Baltimore Ravens

Sep 22 06:15 PM

Spread

Winner

Total

team-logo Baltimore Ravens

team-logo Detroit Lions

Oct 6 06:20 PM

NFL - NFC North - Division Winner (reg. season)

NFL - Futures - NFL - NFC North - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - NFC West - Division Winner (reg. season)

NFL - Futures - NFL - NFC West - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - NFC East - Division Winner (reg. season)

NFL - Futures - NFL - NFC East - Division Winner (reg. season)

Oct 6 06:20 PM

NFL - NFC South - Division Winner (reg. season)

NFL - Futures - NFL - NFC South - Division Winner (reg. season)
 
 

AFC Conference Lines | NFL Football

 
MyBookie AFC Conference Betting

Conference AFC Betting Lines

AFC Conference | American Football Conference
National Football League

 

Road to the Super Bowl

Just like the NFC, the winner of each AFC Division earns a playoff spot. Three Wild Card spots are awarded to the teams with the best rec30th outside the divisional winners.

These six teams then enter a single-elimination playoff format. The ultimate victor of the AFC Championship game punches their ticket to the Super Bowl to face the champion of the NFC.

Many teams in the conference boast high-powered passing attacks and electrifying skill players.

 

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MyBookie’s NFL Lines to Win

Bet the latest NFL daily lines for the AFC Conference winners: Check out how stands today, the Top 5 teams to win here and seek the Super Bowl 60. Don’t forget that those odds are subject to change every week. Last Updated: September 9th

  • Bills +285
  • Ravens +340
  • Chiefs +540
  • Chargers +950
  • Bengals +1100

Moreover, MyBookie offers updated props and odds for every Division during the Regular Season.

If you don’t know, in MyBookie the most popular AFC future bets will always be Division winners, Regular Season win totals and Head-to-Head matchups.

 

Create Your MyBookie Account

Create an account on our Sign-up page and join MyBookie to start winning with the AFC Conference!

Second, follow the steps to complete the form.

Third, check out our betting lines, odds and props for the NFL matchups.

Finally, begin your football plans and strategies with the options that MyBookie has available for you during all season, such as Credit Card or PayPal.

Print Printable AFC Odds

 
 

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All NFL Teams to Win

 
AFC
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Latest NFL Betting News with MyBookie Sports Team

Also, find betting news with the latest AFC lines, tips, and strategies for smarter NFL bets this season with MyBookie.

The Red Flag Report: The Stat You're Ignoring That Will Wreck Your Favorite NFL RB Prop Bet

The Red Flag Report: The Stat You’re Ignoring That Will Wreck Your Favorite NFL RB Prop Bet

Posted: Wednesday, September 10, 2025 5:00, EDT
  If you’re betting an NFL RB Prop Bet this season, there’s one overlooked stat that could blow up your ticket before halftime—and it’s the reason most casual bettors keep losing while sharps keep winning.   The Hidden Red Flags Sabotaging Your NFL RB Prop Bets Spot the hidden traps in NFL RB prop bets—and turn them into your edge … click title for full article.
NFL Week 1 Betting: Is Your Favorite Team a Lock or a Letdown?

NFL Week 1 Betting: Is Your Favorite Team a Lock or a Letdown?

Posted: Tuesday, September 2, 2025 3:15, EDT
Week 1 is funny. Every fan swears this is the year. Preseason highlights roll, the media cranks up the buzz, and suddenly people start asking: Is my team a lock? Most of the time, no. The opening week of the NFL is messy, and if you want an edge in NFL Week 1 betting, you’ve got to ignore the noise. … click title for full article.
 

MyBookie AFC Conference Betting | Betting MyBookie’s AFC Conference Odds

NFL Week Odds: Bet on this American Conference team totals, spreads, lines, and NFL Football futures & specials.